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A RESEARCH AND DEVELOPMENT (R&D) ROADMAP FOR INFLUENZA VACCINES: LOOKING TOWARD THE FUTURE
Moore, Kristine A. et al. | Date Issued: 2021
Author
Moore, Kristine A.
Ostrowsky, Julia T.
Kraigsley, Alison M.
Mehr, Angela
Bresee, Joseph S.
Friede, Martin H.
Gellin, Bruce G.
Golding, Josephine P.
Hart, Peter J.
Moen, Ann
Weller, Charlotte L.
Osterholm, Michael T.
Barclay, Wendy
Cavaleri, Marco
Cohen, Cheryl
Cowling, Benjamin
Cox, Rebecca
Gust, Ian
Innis, Bruce
Kang, Gagandeep
Katz, Jacqueline
Krammer, Florian
Pitisuttithum, Punnee
Post, Diane
Rudenko, Larisa
Siqueira, Marilda Agudo Mendonça Teixeira de
Weir, Jerry
Affilliation
Center for Infectious Disease Research and Policy, University of Minnesota, Minneapolis, MN, USA / Center for Infectious Disease Research and Policy, C315 Mayo Memorial Building, MMC 263, 420 Delaware Street, SE, Minneapolis, MN 55455, USA.
Center for Infectious Disease Research and Policy, University of Minnesota, Minneapolis, MN, USA.
Center for Infectious Disease Research and Policy, University of Minnesota, Minneapolis, MN, USA.
Center for Infectious Disease Research and Policy, University of Minnesota, Minneapolis, MN, USA.
The Global Funders Consortium for Universal Influenza Vaccine Development, The Task Force for Global Health and the US Centers for Disease Control and Prevention, Atlanta, GA, USA.
World Health Organization. Geneva, Switzerland.
The Sabin Vaccine Institute. Washington, D.C., USA.
Wellcome Trust. London, United Kingdom.
Wellcome Trust. London, United Kingdom.
World Health Organization. Geneva, Switzerland.
Wellcome Trust. London, United Kingdom.
Center for Infectious Disease Research and Policy, University of Minnesota. Minneapolis, MN, USA.
University of Ghana. Accra, Ghana.
Imperial College London. London, United Kingdom.
European Medicines Agency. Amsterdam, the Netherlands.
National Institute for Communicable Diseases and University of the Witwatersrand. Johannesburg, South Africa.
University of Hong Kong. Hong Kong.
University of Bergen. Bergen, Norway.
University of Melbourne. Melbourne, Australia.
PATH Center for Vaccine Innovation & Access. Washington, D.C., USA.
Christian Medical College. Vellore, India.
US Centers for Disease Control & Prevention (Retired). Atlanta, GA, USA.
Icahn School of Medicine at Mount Sinai. New York City, NY, USA.
Mahidol University. Bangkok, Thailand.
National Institutes of Health. Bethesda, MD, USA.
Institute of Experimental Medicine. St. Petersburg, Russia.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Food and Drug Administration. Silver Spring, MD, USA.
Abstract
Improved influenza vaccines are urgently needed to reduce the burden of seasonal influenza and to ensure a rapid and effective public-health response to future influenza pandemics. The Influenza Vaccines Research and Development (R&D) Roadmap (IVR) was created, through an extensive international stakeholder engagement process, to promote influenza vaccine R&D. The roadmap covers a 10- year timeframe and is organized into six sections: virology; immunology; vaccinology for seasonal influenza vaccines; vaccinology for universal influenza vaccines; animal and human influenza virus infection models; and policy, finance, and regulation. Each section identifies barriers, gaps, strategic goals, milestones, and additional R&D priorities germane to that area. The roadmap includes 113 specific R&D.
Keywords in Portuguese
Gripe
Preparação para pandemia
 
Keywords
Influenza
Pandemic preparedness
 
Publisher
Elsevier
Citation
MOORE, Kristine A. et al. A Research and Development (R&D) roadmap for influenza vaccines: Looking toward the future. Vaccine, v. 39, p. 6573-6584, Sept. 2021.
DOI
10.1016/j.vaccine.2021.08.010
ISSN
0264-410X