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Title: Estudo bacteriológico de escarros de leprosos-tuberculosos em tratamento com a Estreptomicina
Authors: Araujo, H. C. de Souza
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Abstract: Fourteen samples of sputum from fourteen lepers with pulmonary tuberculosis, were treated by PETROFF method and its sediments were smeared on LOEWENSTEIN medium and incubated at 37°C. These fourteen patients are under treatment by Streptomycin. They are advanced cases of active leprosy associated with pulmonary tuberculosis, according to X ray diagnosis. Between 15 to 45 days thirteen out of fourteen (92,85%) sputa gave cultures of acid-fast bacilli with all characteristics of KOCH'S bacillus, eugonic type. Nine out of thirteen positive cases produced eugonic colonies in all ten tubes smeared with each sample. These facts proved that Streptomycin did not affect the pulmonary flora. Three out of fourteen patients died within two months after positive cultures of KOCH'S bacillus. New fact - Three out of those thirteen positive patients gave non-chromogenic cultures, eugonic type, associated with chromogenic ones, quite similar to cultures of acid-fast bacilli isolated previously by the author from leprous material. One of the three patients who died showed in smear of fresh sputum only characteristics globies (globies of MARCHOUX not globi of NEISSER) of HANSEN'S Bacillus. Probably he died from leprous-pneumonia. The eugonic type cultures are being inoculated in guinea-pigs and the choromogenic ones, similar to leprosy-culture, will be inoculated in white rats and mice.
keywords: Estudo bacteriológico
Tratamento com Estreptomicina
Issue Date: 1948
Publisher: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
Citation: ARAUJO, H. C. de Souza. Estudo bacteriológico de escarros de leprosos-tuberculosos em tratamento com a Estreptomicina. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 46, n. 4, p. 1 - 3, 1948.
DOI: 10.1590/S0074-02761948000400002
ISSN: 0074-0206
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos
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