Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/551
Title: HIV Infection in 567 Active Pulmonary Tuberculosis Patients in Brazil
Authors: Kritski, Afranio L.
Barroso, Eduardo Werneck
Vieira, Maria Armandas
Carvalho, Anna C. C.
Carvalho, Carlos Eduardos
Souza, Roberto Bravo de
Andrade, Geraldo de Noronha
Castro Filho, Bernardo Galvão
Castilho, Euclides Ayres de
Hearst, Norman
Affilliation: Universidade Federal do Rio de Janeiro. Instituto do Coração e Pulmão. Rio de Janeiro, RJ, Brasil.
Universidade Federal do Rio de Janeiro. Instituto do Coração e Pulmão. Rio de Janeiro, RJ, Brasil.
Universidade Federal do Rio de Janeiro. Instituto do Coração e Pulmão. Rio de Janeiro, RJ, Brasil.
Universidade Federal do Rio de Janeiro. Instituto do Coração e Pulmão. Rio de Janeiro, RJ, Brasil.
Universidade Federal do Rio de Janeiro. Instituto do Coração e Pulmão. Rio de Janeiro, RJ, Brasil.
Universidade Federal do Rio de Janeiro. Instituto do Coração e Pulmão. Rio de Janeiro, RJ, Brasil.
Universidade Federal do Rio de Janeiro. Instituto do Coração e Pulmão. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
University of California. Center for AIDS Prevention Studies. San Francisco, California, USA.
Abstract: Summary: We studied 567 patients with active pulmonary tuberculosis (APT) in Rio de Janeiro, Brazil, by using a standardized questionnaire and by testing blood for HIV antibodies. The rate of HI V infection was 3.9% in 1987,4.8% in 1988, and 5.2% in 1989, and did not differ by sex. It was highest (7.4%) in the 15- to 39-year age group. There was no difference between patients infected and not infected by HIV with regard to education, income, housing, or employment. Among all patients with definite HIV risk behavior, the HIV infection rate was 23.3%, rising to 31.2% among homo/bisexual men and 36.4% among intravenous drug users, and the rate was 6.5% for blood-transfusion recipients. Among patients who denied risk behavior, the rate was 1.2%. Generalized lymphadenopathy and oral candidiasis occurred with greater frequency among HIV-infected patients (p < 0.0001). Applying the World Health Organization 1985 clinical criteria and revised case definition for AIDS, we found, respectively, sensitivities of 34% and 76.9% and specificities of 31% and 26.3%; in the Rio de Janeiro environment, these clinical criteria without HIV serology should not be adopted for tuberculosis patients. For chest radiographs, a significant association was found between HIV infection and the occurrence of atypical images (p = 0.0001), and hilar and/or mediastinal adenopathy (p = 0.0002) and absence of cavities (p = 0.0003). A PPD (purified protein derivative) skin test induration of <5 mm was identified in 53% of the HIV-positive cases and in 31.3% of the HIV-negative cases. Only 11.5% of HIV-infected APT patients met the Centers for Disease Control 1987 AIDS criteria.
keywords: Brazil
HIV
Tuberculosis
Issue Date: 1993
Publisher: Raven Press, Ltd, New York
Citation: KRITSKI, Afranio L., et al. HIV Infection in 567 Active Pulmonary Tuberculosis Patients in Brazil. Journal of Acquired Immune Deficiency Syndromes, v.6. n.9, 1993.
ISSN: 10779450
Copyright: open access
Appears in Collections:ICICT - Artigos de Periódicos

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