| Author | Oliveira, Roseli Fernandes | |
| Author | Andrade, Zilton de Araújo | |
| Access date | 2012-09-11T19:49:22Z | |
| Available date | 2012-09-11T19:49:22Z | |
| Document date | 2001 | |
| Citation | OLIVEIRA, R. F.; ANDRADE, Z. A. Worm load and septal fibrosis of the liver in Capillaria hepatica-infected rats. Memórias do Instituto Oswaldo Cruz, v. 96, n. 7, p. 1001-1003, Oct. 2001. | pt_BR |
| ISSN | 0074-0276 | |
| URI | https://www.arca.fiocruz.br/handle/icict/5510 | |
| Language | eng | pt_BR |
| Rights | open access | |
| Title | Worm load and septal fibrosis of the liver in Capillaria hepatica-infected rats. | pt_BR |
| Type | Article | pt_BR |
| Abstract | Inocula, varying from 15 to 1,000 embryonated Capillaria hepatica eggs, were administered to young
adult rats by gastric tube, in an attempt to investigate the influence of worm load in the production of
septal fibrosis of the liver. Low doses of 15, 30 or 50 eggs were sufficient to produce septal fibrosis, but
it appeared with variable degrees of intensity and always with focal distribution. Septal fibrosis
became diffuse, progressive with time, and already well developed 40 days after infection, when 100
eggs or more were administered. However, higher inocula (200, 500 and 1,000 eggs) did not intensify
septal fibrosis, although the number of parasitic focal lesions proportionally augmented. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Subject | Capillaria hepatica | pt_BR |
| Subject | Septal hepatic fibrosis | pt_BR |
| Subject | Worm load | pt_BR |
| DeCS | Capillaria | pt_BR |
| DeCS | Infecções por Enoplida/complicações | pt_BR |
| DeCS | Cirrose Hepática Experimental/parasitologia | pt_BR |
| DeCS | Hepatopatias Parasitárias/parasitologia | pt_BR |
| DeCS | Animais | pt_BR |
| DeCS | Modelos Animais de Doenças | pt_BR |
| DeCS | Feminino | pt_BR |
| DeCS | Cirrose Hepática Experimental/patologia | pt_BR |
| DeCS | Hepatopatias Parasitárias/patologia | pt_BR |
| DeCS | Masculino | pt_BR |
| DeCS | Ratos | pt_BR |
| DeCS | Ratos Wistar | pt_BR |
