Author | Silva, Moacir Paranhos | |
Author | Pontes-de-Carvalho, Lain Carlos | |
Author | Oliveira, Geraldo Gileno de Sá | |
Author | Nascimento, Eliane Góes | |
Author | dosSantos, Washington Luis Conrado | |
Access date | 2012-09-19T18:02:35Z | |
Available date | 2012-09-19T18:02:35Z | |
Document date | 2001 | |
Citation | PARANHOS-SILVA, M. et al. Skin reactions to thimerosal and Leishmania in dogs from a leishmaniasis endemic area: it is better to keep them apart. Memórias do Instituto Oswaldo Cruz, v. 96, n. 5, p. 679-81, July 2001. | pt_BR |
ISSN | 0074-0276 | |
URI | https://www.arca.fiocruz.br/handle/icict/5529 | |
Language | eng | pt_BR |
Rights | open access | |
Title | Skin reactions to thimerosal and Leishmania in dogs from a leishmaniasis endemic area: it is better to keep them apart | pt_BR |
Type | Article | pt_BR |
Abstract | Positive Montenegro's skin test is a delayed type hypersensitivity reaction widely used as indicative of previous infection with Leishmania in both humans and dogs. Montenegro's antigen consists of a crude Leishmania antigen solution, usually containing thimerosal as preserving agent. In this work it is shown that a large proportion of dogs (11 out of 56) examined in an endemic area of leishmaniasis presented induration at the site of injection of a diluent containing thimerosal alone. This clearly demonstrates that thimerosal leads to a high number of false positive skin reactions in dogs and that its use in Montenegro's skin test antigenic preparations should be avoided | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Centro de Referência em Doenças Endêmicas Pirajá da Silva. Jequié, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Subject | Montenegro’s skin test | pt_BR |
Subject | Leishmania | pt_BR |
Subject | Delayed type hypersensitivity | pt_BR |
Subject | Thimerosal | pt_BR |
Subject | Canine visceral leishmaniasis | pt_BR |
DeCS | Doenças do Cão/diagnóstico | pt_BR |
DeCS | Leishmania/imunologia | pt_BR |
DeCS | Leishmaniose/veterinária | pt_BR |
DeCS | Conservantes Farmacêuticos/efeitos adversos | pt_BR |
DeCS | Pele/efeitos de drogas | pt_BR |
DeCS | Timerosal/efeitos adversos | pt_BR |
DeCS | Animais | pt_BR |
DeCS | Brasil/epidemiologia | pt_BR |
DeCS | Doenças do Cão/epidemiologia | pt_BR |
DeCS | Doenças do Cão/imunologia | pt_BR |
DeCS | Doenças Endêmicas | pt_BR |
DeCS | Reações Falso-Positivas | pt_BR |
DeCS | Hipersensibilidade/imunologia | pt_BR |
DeCS | Hipersensibilidade/veterinária | pt_BR |
DeCS | Leishmaniose/diagnóstico | pt_BR |
DeCS | Leishmaniose/epidemiologia | pt_BR |
DeCS | Pele/imunologia | pt_BR |
DeCS | Pele/patologia | pt_BR |
DeCS | Testes Cutâneos | pt_BR |