Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/559
Title: Human immunodeficiency virus/acquired immunodeficiency syndrome and tropical diseases: a brazilian perspective
Authors: Morgado, Mariza Gonçalves
Barcellos, Christovam de Castro
Pina, Maria de Fátima Rodrigues Pereira de
Bastos, Francisco Inácio Pinkusfeld Monteiro
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Centro de Informação Científica e Tecnológica. Departamento de Informações em Saúde. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Centro de Informação Científica e Tecnológica. Departamento de Informações em Saúde. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Centro de Informação Científica e Tecnológica. Departamento de Informações em Saúde. Rio de Janeiro, RJ, Brasil.
Abstract: The paper summarizes recent findings on the epidemiology and pathogenesis of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/Aids), highlighting the role of co-infections with major tropical diseases. Such co-infections have been studied in the Brazilian context since the beginning of the Aids epidemic and are expected to be more frequent and relevant as the Aids epidemic in Brazil proceeds towards smaller municipalities and the countryside, where tropical diseases are endemic. Unlike opportunistic diseases that affect basically the immunocompromised host, most tropical diseases, as well as tuberculosis, are pathogenic on their own, and can affect subjects with mild or no immunossuppression. In the era of highly active anti-retroviral therapies (HAART), opportunistic diseases seem to be on decrease in Brazil, where such medicines are fully available. Benefiting from HAART in terms of restoration of the immune function, putative milder clinical courses are expected in the future for most co-infections, including tropical diseases. On the other hand, from an ecological perspective, the progressive geographic diffusion of Aids makes tropical diseases and tuberculosis a renewed challenge for Brazilian researchers and practitioners dealing with HIV/Aids in the coming years.
Keywords: Acquired immunodeficiency syndrome
Human immunodeficiency virus
HIV/Aids
Co-infections
Brazil
Issue Date: 2000
Publisher: Fundação Oswaldo Cruz
Citation: MORGADO, Mariza Gonçalves et al. Human immunodeficiency virus/acquired immunodeficiency syndrome and tropical diseases: a brazilian perspective. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 95, suppl. I, p. 145-151, 2000.
ISSN: 0074-0276
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos
ICICT - Artigos de Periódicos

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