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THE UNRESOLVED QUESTION ON COVID‐19 VIRUS ORIGIN: THE THREE CARDS GAME?
Borsetti, Alessandra et al. | Date Issued: 2022
Author
Borsetti, Alessandra
Scarpa, Fabio
Maruotti, Antonello
Divino, Fabio
Ceccarelli, Giancarlo
Giovanetti, Marta
Ciccozzi, Massimo
Affilliation
National HIV/AIDS Research Center, Istituto Superiore di Sanità, Rome, Italy.
Department of Veterinary Medicine, University of Sassari, Sassari, Italy.
Department GEPLI, Libera Università Maria SS Assunta, Rome, Italy / Department of Mathematics, University of Bergen, Bergen, Norway.
Department of Biosciences, Laboratory of Biostatistics and Computational Epidemiology, University of Molise, Campobasso, Italy.
Department of Public Health and Infectious Diseases, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil / Universidade Federal de Minas Gerais. Laboratório de Genética Celular e Molecular, ICB, Belo Horizonte, MG, Brasil.
Medical Statistics and Epidemiology Unit, Department of Medicine, Campus Bio‐Medico University, Rome, Italy.
Abstract
The ongoing discussion about the real origin of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) feeds acrimonious debates. Where did SARS‐CoV‐2 come from? Was SARS‐CoV‐2 transmitted in the wild from an animal to a person before exploding in Wuhan or was it an engineered virus that escaped from research or a laboratory in Wuhan? Right now, we still don't know enough whether SARS‐CoV‐2 is human‐made or not, and lab‐leak theories remain essentially speculative. Many recent studies have pointed out several plausible scenarios. Anyhow, currently, even if suspicions by some about the possibility of lab‐leak hypothesis still remain, the consensus view is that the pandemic probably started from a natural source and, to determine the real origin of the SARS‐CoV‐2 virus, further research is needed.
Keywords in Portuguese
Coronavirus
Epidemiologia
Pandemia
SARS coronavirus
Classificação de vírus
 
Keywords
Coronavirus
Epidemiology
Pandemics
SARS coronavirus
Virus classification
 
Publisher
Wiley
Citation
BORSETTI, Alessandra et al. The unresolved question on COVID‐19 virus origin: The three cards game?. Journal of Medical Virology, v. 94, p. 1257-1260, 2022.
DOI
10.1002/jmv.27519
ISSN
1096-9071