| Author | Fernandez, José Carlos Couto | |
| Author | Morgado, Mariza Gonçalves | |
| Author | Bongertz, Vera | |
| Author | Tanuri, Amilcar | |
| Author | Andrade, Tarcisio Mattos de | |
| Author | Alves, Carlos Roberto Brites | |
| Author | Castro Filho, Bernardo Galvão | |
| Access date | 2012-10-04T20:34:19Z | |
| Available date | 2012-10-04T20:34:19Z | |
| Document date | 1999 | |
| Citation | COUTO-FERNANDEZ, J.C. et al. HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics. Journal of Acquired Immune Deficience Syndromes v. 22, n. 3, p. 288-93, nov. 1999. | pt_BR |
| ISSN | 1525-4135 | |
| URI | https://www.arca.fiocruz.br/handle/icict/5646 | |
| Language | eng | pt_BR |
| Rights | open access | |
| Title | HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics | pt_BR |
| Type | Article | pt_BR |
| Abstract | To investigate the prevalence of the HIV-1 subtypes in different populations from Salvador, Bahia, Brazil, blood samples from 72 HIV-1-seropositive injecting drug users (IDUs) and 62 individuals infected sexually were analyzed using the heteroduplex mobility assay (HMA). In the IDU group, 89.5% were classified as subtype B, 3% as subtype F, and 7.5% showed a B/F HMA profile. In the sexual transmission (ST) group, 95% were identified as B subtype, 3.4% showed a B/F profile, and 1.6% a B/C/E HMA profile. All Brazilian samples that showed multiple reactivities in the HMA analysis clustered on sequencing with B North American/ European HIV-1 isolates in the phylogenetic analysis, whereas the F subtypes clustered with F Brazilian HIV-I isolates. Serologic reactivities of IDU's sera were examined using a panel of synthetic V3 loop peptides representative of the different HIV-1 subtypes. No difference in serologic reactivity between F and B subtype plasma could be observed. Predominance of HIV-I subtype B was identified in both study groups, whereas subtype F was detected only among IDUs in a frequency lower than described for other Brazilian regions. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Departamento de Genética. Rio de Janeiro, RJ, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Centro de Tratamento do Abuso de Drogas. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Laboratorio de Retrovirologia Prof. Edgard Santos Hospital. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Subject | HIV-1 | pt_BR |
| Subject | Subtypes | pt_BR |
| Subject | Diversity | pt_BR |
| Subject | Brazil | pt_BR |
| DeCS | Variação Antigênica | pt_BR |
| DeCS | Infecções por HIV/virologia | pt_BR |
| DeCS | HIV-1/classificação | pt_BR |
| DeCS | Adolescente | pt_BR |
| DeCS | Adulto | pt_BR |
| DeCS | África/etnologia | pt_BR |
| DeCS | Grupo com Ancestrais do Continente Africano | pt_BR |
| DeCS | Brasail | pt_BR |
| DeCS | Ensaio de Imunoadsorção Enzimática | pt_BR |
| DeCS | Feminino | pt_BR |
| DeCS | Infecções por HIV/imunologia | pt_BR |
| DeCS | Infecções por HIV/transmissão | pt_BR |
| DeCS | HIV-1/imunologia | pt_BR |
| DeCS | Análise Heteroduplex | pt_BR |
| DeCS | Humanos | pt_BR |
| DeCS | Masculino | pt_BR |
| DeCS | Meia-Idade | pt_BR |
| DeCS | Filogenia | pt_BR |
| DeCS | Reação em Cadeia da Polimerase | pt_BR |
| DeCS | Comportamento Sexual | pt_BR |
| DeCS | Fatores Socioeconômicos | pt_BR |
| DeCS | Abuso de Substâncias por Via Intravenosa/complicações | pt_BR |
| xmlui.metadata.dc.subject.ods | 10 Redução das desigualdades | |
