Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/5696
Title: Trypanosoma cruzi strains: behavior after passage into authoctonous or foreign species of traitomine (biological and biochemical patterns).
Authors: Magalhães, Juracy Barbosa
Andrade, Sonia Gumes
Sherlock, Ítalo Rodrigues de Araújo
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Abstract: The behavior of T. cruzi strains from S. Felipe-BA (19 SF, 21 SF and 22 SF) classified as Type II Zymodeme 2, was investigated after passage through the authoctonous (P. megistus) and foreign vectors (T. infestans and R. prolixus). For each strain Swiss mice were infected: I--with blood forms (control); II--with metacyclic forms (MF) from P. megistus; III--with MF from T. infestans; IV--with MF from R. prolixus. Inocula: MF from the three species of triatomine, 60 to 120 days after feeding in infected mice, adjusted to 10(4). Biological behavior in mice (parasitemia, morphology, mortality, virulence and pathogenicity) after passage through triatomine was compared with data from the same strain in control mice. Isoenzymic electrophoresis (ASAT, ALAT, PGM, GPI) were also performed after culture into Warren medium. The three strains maintained the isoenzyme profiles (zymodeme 2), in the control groups and after passages through different species of triatomine. Biological characterization disclosed Type II strains patterns for all groups. An increased virulence was observed with the 22 SF strain isolated from P. megistus and T. infestans and higher levels of parasitemia and predominance of slender forms in mice inoculated with the 19 SF and 21 SF from these same species. Results indicate that the passage through the two species T. infestans and P. megistus had a positive influence on the virulence of the regional strains of S. Felipe, regardless of being autocthonous (P. megistus) or foreign to the area (T. infestans).
Keywords: Trypanosoma cruzi
T. cruzi strains
Biological characters
Biodermes
Zymodemes
Vctor species
Triatomine
DeCS: Triatominae/parasitologia
Trypanosoma cruzi/fisiologia
Animais
Doença de Chagas/sangue
Doença de Chagas/parasitologia
Humanos
Isoenzimas/metabolismo
Camundongos
Fatores de Tempo
Trypanosoma cruzi/enzimologia
Trypanosoma cruzi/patogenicidade
Virulência
Issue Date: 1996
Citation: MAGALHÃES, J.B.; ANDRADE, S.G.; SHERLOCK, I. Trypanosoma cruzi strains: behavior after passage into authoctonous or foreign species of traitomine (biological and biochemical patterns). Revista do Instituto de Medicina Tropical de São Paulo, v. 38, n. 1, p. 23-8, jan.-feb. 1996.
ISSN: 0036-4665
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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