Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/5698
Title: Repair of schistosomal intestinal vascular lesions after curative treatment.
Authors: Silva, Luciana Cristina S.
Andrade, Zilton de Araújo
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Abstract: The process of repairing intestinal vascular lesions induced by schistosomiasis in mice was studied before and after curative chemotherapy, by means of histopathology coupled with injections of the mesenteric veins with India ink or plastic, in this case followed by corrosion in strong acid. The granulomas were avascular, mainly formed while within blood vessels, and were associated with distortion of the intestinal vasculature in their proximity, represented by tortuosities, focal dilatation, narrowing, and anastomosis of the mucosal and submucosal veins. Two to four months after cure of schistosomiasis involuting granulomas were seen to be slowly vascularized, a process going from the periphery toward the center of the granulomas. No intravascular granulomas were seen four months after treatment. The previously distorted mucosal and submucosal veins gradually regained their normal appearance, only a slight tortuosity remaining.
Keywords: Schistosoma mansoni
Vascular lesions
Repair
Intestinal Schistosomiasis
DeCS: Granuloma/parasitologia
Esquistossomose mansoni/patologia
Animais
Feminino
Granuloma/quimioterapia
Granuloma/patologia
Enteropatias/quimioterapia
Enteropatias/parasitologia
Masculino
Camundongos
Esquistossomose mansoni/quimioterapia
Issue Date: 1995
Citation: SILVA, L.; ANDRADE, Z.A. Repair of schistosomal intestinal vascular lesions after curative treatment. Memórias do Instituto Oswaldo Cruz, v. 90, n. 3, p. 401-5, may-jun. 1995.
ISSN: 0074-0276
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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