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SOIL SAMPLES FROM SPOROTRICHOSIS TRANSMISSION BELT AREA: SEARCHING FOR FUNGAL SPECIES AND THEIR ANTAGONISTIC ACTIVITY AGAINST SPOROTHRIX BRASILIENSIS
Costa, Gisela Lara da et al. | Date Issued: 2022
Author
Costa, Gisela Lara da
Ferreira, Isabella Escórcio
Moreira, Danielly Corrêa
Marinho, Anna
Almeida, Adilson Benedito de
Pereira, Sandro Antônio
Borba, Cintia Moraes
Oliveira, Manoel Marques Evangelista
Affilliation
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Pós-doutorado em Pesquisa Clínica em Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos. Rio de Janeiro, RJ, Brasil.
Abstract
Since 1998, the state of Rio de Janeiro, Brazil, has become a public health problem regarding sporotrichosis, a disease caused by Sporothrix spp. involving contact with infected cats. Efforts to isolate these species from environmental sources are not always successful. In our study, soil from residences situated in cities of Rio de Janeiro where cats with sporotrichosis live was collected and cultured an attempt to isolate Sporothrix spp. but it was not successful. However, other saprophytic fungal species were isolated from soil and identified and among them Purpureocillium lilacinum was the most frequent. From there, we decided to study the in vitro interaction of this species with S. brasiliensis, the principal agent that causes sporotrichosis in this state. The results showed that ten isolates of P. lilacinum inhibited the radial mycelial growth of S. brasiliensis with different percentage of inhibition. The interaction between them revealed the pattern described as overgrowth by antagonist. In conclusion, our data suggest that fungal species with very fast growth and capable of producing metabolites could hinder the growth of Sporothrix spp., it also opens the way for the identification of secondary metabolites with biological activity that could be tested against pathogenic fungi.
Keywords in Portuguese
Meio Ambiente
Solo
Interação fúngica
Caracterização fenotípica
Sporothrix spp
Esporotricose
Purpureocillium lilacinum
 
Keywords
Environment
Soil
Fungal interaction
Phenotypic characterization
Sporothrix spp
Sporotrichosis
Purpureocillium lilacinum
 
Publisher
Frontiers Media
Citation
COSTA, Gisela Lara da et al. Soil samples from sporotrichosis transmission belt area: Searching for fungal species and their antagonistic activity against Sporothrix brasiliensis. Frontiers in Cellular and Infection Microbiology, v. 12, 1033969, p. 1 - 8, Dec. 2022.
DOI
10.3389/fcimb.2022.1033969
ISSN
2235-2988