Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/5740
Title: Induced tolerance to Schistosoma mansoni antigens modulates periovular granuloma.
Authors: Sadigursky, Moysés
Falangola, Maria de Fátima
Santos, Rosella de Oliveira
Cardoso, Silvia Andrade
David, John R
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Harward Medical School. Boston, USA
Abstract: Immunological tolerance to Schistosoma mansoni antigens induced by oral exposure of neonatal and adult mice to adult worm, soluble egg and polysaccharide antigens conducted to modulated periovular granuloma of infected mice. However the tolerance do not interfere in the infection. The estimative population and subpopulation of lymphocytes in the spleen of tolerized (not infected) animals do not differ from normal animals but Lyt 2.2 reactive lymphocytes to Schistosoma antigens was demonstrated in the tolerized animals.
DeCS: Antígenos de Helmintos/imunologia
Granuloma/patologia
Schistosoma mansoni/imunologia
Esquistossomose mansoni/patologia
Administração Oral
Animais
Anticorpos Anti-Helmínticos/biossíntese
Antígenos de Helmintos/administração & dosagem
Tolerância Imunológica
Imunização
Fígado/patologia
Camundongos
Esquistossomose mansoni/imunologia
Issue Date: 1987
Citation: SADIGURSKY, M. et al. Induced tolerance to Schistosoma mansoni antigens modulates periovular granuloma. Memórias do Instituto Oswaldo Cruz, v. 82, Suppl 4, p. 269-71, 1987.
ISSN: 0074-0276
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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