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MITOCHONDRIA PUSH PLATELETS PAST THEIR PRIME
Mitochondrial Permeability Transition Pore (MPTP)
Demonstrated that Cyclophilin D (CypD)
Affilliation
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
The University of Utah. UT, USA.
The University of Utah. UT, USA.
Abstract
In the February 1 issue of Blood, Jobe and colleagues elucidated the function of the mitochondrial permeability transition pore (MPTP), in platelet activation and demonstrated that cyclophilin D (CypD), a regulator of MPTP formation, is a critical factor in the procoagulant response to strong agonists.
Keywords
MitochondriaMitochondrial Permeability Transition Pore (MPTP)
Demonstrated that Cyclophilin D (CypD)
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