| Author | Silva, Marcus Tulius T. | |
| Author | Harab, Ramza Cabral | |
| Author | Leite, Ana Cláudia | |
| Author | Schor, Doris | |
| Author | Araújo, Abelardo | |
| Author | Andrada-Serpa, Maria José | |
| Access date | 2023-04-03T14:57:04Z | |
| Available date | 2023-04-03T14:57:04Z | |
| Document date | 2007 | |
| Citation | SILVA, Marcus Tulius T. et al. Human T lymphotropic virus type 1 (HTLV-1) proviral load in asymptomatic carriers, HTLV-1-associated myelopathy/tropical spastic paraparesis, and other neurological abnormalities associated with HTLV-1 infection. Clinical Infectious Diseases, v. 44, n. 5, p. 689-692, Mar. 2007. | en_US |
| ISSN | 1058-4838 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/57660 | |
| Sponsorship | We thank Marcos A. M. Scheiner and Beatriz J. Pereira Vaz for the first experiments of proviral load. We thank Prof. William Hall and Dr. Carla Vorsatz for their review of the English in this manuscript. Financial support. Brazilian National Research Council (CNPq), Fundac¸a˜o Oswaldo Cruz, and Brazilian Health Ministry. Potential conflicts of interest. All authors: no conflicts. | en_US |
| Language | eng | en_US |
| Publisher | Oxford University Press | en_US |
| Rights | open access | en_US |
| Title | Human T lymphotropic virus typ7e 1 (HTLV-1) proviral load in asymptomatic carriers, HTLV-1-associated myelopathy/tropical spastic paraparesis,1 and other neurological abnormalities associated with HTLV-1 infection | en_US |
| Type | Article | en_US |
| DOI | 10.1086/510679 | |
| Abstract | Recent reports have demonstrated that human T lymphotropic virus type 1 (HTLV-1) is associated with other neurological abnormalities in addition to HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). It has been well established that high HTLV-1 proviral loads are associated with the development of HAM/TSP. We now demonstrate, for the first time, to our knowledge, that HTLV-1 proviral loads in patients with other neurological abnormalities are also significantly higher than in asymptomatic HTLV-1 carriers. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Reference Center for Neuroinfection Diseases. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Laboratory of Virology. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Reference Center for Neuroinfection Diseases and HTLV. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Laboratory of Virology. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Reference Center for Neuroinfection Diseases and HTLV. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Laboratory of Virology. Reference Center for Neuroinfection Diseases and HTLV. Rio de Janeiro, RJ, Brazil. | en_US |
| Subject | Human T lymphotropic virus type 1 (HTLV-1) | en_US |
| Subject | Asymptomatic Carriers | en_US |
| Subject | Neurological Abnormalities | en_US |
| Subject | HTLV-1 Infection | en_US |
| e-ISSN | 1537-6591 | |
