Author | Carmo, Maria Auxiliadora Vieira do | |
Author | Grossmann, Soraya de Mattos Camargo | |
Author | Teixeira, Rosângela | |
Author | Oliveira, Guilherme Corrêa de | |
Author | Carmo, Maria Auxiliadora Vieira do | |
Access date | 2023-07-27T19:47:12Z | |
Available date | 2023-07-27T19:47:12Z | |
Document date | 2010 | |
Citation | GROSSMANN, Soraya de Mattos Camargo et al. Detection of HCV RNA in saliva does not correlate with salivary flow or xerostomia in patients with chronic hepatitis C. Oral Surg Oral Med Oral Pathol Oral Radiol Endod., v. 109, n. 6, p. 851-856. doi: 10.1016/j.tripleo.2010.02.012. | en_US |
ISSN | 1079-2104 | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/59818 | |
Language | eng | en_US |
Publisher | Elsevier. | en_US |
Rights | restricted access | en_US |
Title | Detection of HCV RNA in saliva does not correlate with salivary flow or xerostomia in patients with chronic hepatitis C | en_US |
Type | Article | en_US |
DOI | 10.1016/j.tripleo.2010.02.012 | |
Abstract | Objective. The objective of this study was to investigate the prevalence of hepatitis C virus (HCV) RNA in saliva and its possible association with xerostomia and hyposalivation in patients with chronic hepatitis C. Study design. One hundred and thirty-six patients with confirmed diagnosis of chronic hepatitis C were prospectively analyzed before HCV treatment. The prevalence of xerostomia and hyposalivation was clinically evaluated. HCV RNA was investigated in saliva samples by qualitative PCR test. Univariate and multivariate analyses were used to verify associations. Results. Xerostomia was reported by 48 (35.3%) patients, whereas hyposalivation was observed in 26 (19.1%). HCV RNA was positive in the saliva of 53 (39.0%) patients. An association among HCV RNA-positive saliva with xerostomia or hyposalivation was not observed. Conclusion. Our results demonstrate that the detection of HCV in saliva does not correlate with salivary flow or xerostomia in patients with chronic hepatitis C. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: 851-856 | en_US |
Affilliation | Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery and Pathology. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Universidade Federal de Minas Gerais. School of Medicine. Department of Internal Medicine. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery and Pathology. Belo Horizonte, MG, Brazil | en_US |
Embargo date | 2030-12-31 | |