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NEW APPROACHES TO EVALUATE THE CYTOTOXIC POTENTIAL OF LEISHMANICIDAL DRUGS USING HUMAN PERIPHERAL BLOOD
Carvalho, Andréa Teixeira de et al. | Date Issued: 2023
Author
Carvalho, Andréa Teixeira de
Cota, Betania Barros
Murta; Silvane Maria Fonseca
Pereira, Victória Hellena Silva
Pascoal, Vanessa Peruhype Magalhães
Souza-Fagundes, Elaine Maria de
Affilliation
Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil.
Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Genômica Funcional de Parasitos. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Instituto René Rachou. Grupo Integrado de Pesquisas em Biomarcadores. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Instituto René Rachou. Grupo Integrado de Pesquisas em Biomarcadores. Belo Horizonte, MG, Brazil
Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Fisiologia e Biofísica. Belo Horizonte, MG, Brazil
Keywords
Leishmaniasis
neglected disease
drug discovery
leishmanicides
whole blood
immunotoxicity
chemoimmunotherapeutic
preclinical assays
3R
predicitive assay
 
Publisher
Springer
Citation
CARVALHO, Andrea Teixeira de et al. New Approaches to Evaluate the Cytotoxic Potential of Leishmanicidal Drugs Using Human Peripheral Blood. Biomarkers in Toxicology, p 909–936, 2023. In: PATEL, V.B; PREEDY, V.R; RAJENDRAM, R. (eds) Biomarkers in Toxicology. Biomarkers in Disease: Methods, Discoveries and Applications. Springer, Cham. https://doi.org/10.1007/978-3-031-07392-2_55