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https://www.arca.fiocruz.br/handle/icict/62836
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2030-12-31
Sustainable Development Goals
03 Saúde e Bem-EstarCollections
- INI - Artigos de Periódicos [3505]
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OPHTHALMIC MANIFESTATIONS OF MONKEYPOX VIRUS INFECTION: A CASES SERIES
Author
Affilliation
Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Infectious Ophthalmology Laboratory. Rio de Janeiro, RJ, Brazil.
Neuroscience Research Group. NeuroVitae Center for Neuroscience. Translational Medicine Institute. School of Medicine and Health Sciences. Universidad del Rosario. Bogotá, Colombia.
Neuroscience Research Group. NeuroVitae Center for Neuroscience. Translational Medicine Institute. School of Medicine and Health Sciences. Universidad del Rosario. Bogotá, Colombia.
Neuroscience Research Group. NeuroVitae Center for Neuroscience. Translational Medicine Institute. School of Medicine and Health Sciences. Universidad del Rosario. Bogotá, Colombia.
Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Infectious Ophthalmology Laboratory. Rio de Janeiro, RJ, Brazil.
Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Infectious Ophthalmology Laboratory. Rio de Janeiro, RJ, Brazil.
Neuroscience Research Group. NeuroVitae Center for Neuroscience. Translational Medicine Institute. School of Medicine and Health Sciences. Universidad del Rosario. Bogotá, Colombia.
Neuroscience Research Group. NeuroVitae Center for Neuroscience. Translational Medicine Institute. School of Medicine and Health Sciences. Universidad del Rosario. Bogotá, Colombia.
Neuroscience Research Group. NeuroVitae Center for Neuroscience. Translational Medicine Institute. School of Medicine and Health Sciences. Universidad del Rosario. Bogotá, Colombia.
Neuroscience Research Group. NeuroVitae Center for Neuroscience. Translational Medicine Institute. School of Medicine and Health Sciences. Universidad del Rosario. Bogotá, Colombia.
Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Infectious Ophthalmology Laboratory. Rio de Janeiro, RJ, Brazil.
Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Infectious Ophthalmology Laboratory. Rio de Janeiro, RJ, Brazil.
Neuroscience Research Group. NeuroVitae Center for Neuroscience. Translational Medicine Institute. School of Medicine and Health Sciences. Universidad del Rosario. Bogotá, Colombia.
Abstract
This retrospective case series aims to describe the ophthalmic manifestations of the Monkeypox virus infection in seven patients evaluated in two countries of South America (Colombia and Brazil). Two had skin lesions in the eyelid, and five had conjunctivitis. None had intraocular involvement. Three of seven patients had a history of Human Immunodeficiency Virus infection, and all patients had lesions in the genital region, suggesting sexual-contact transmission. In 6 of 7 cases, conjunctival RT-PCR was positive for the Monkeypox virus, including one case without conjunctival vesicles. In all cases, lesions resolved without complications, and just two required antiviral treatment. All patients demonstrated improvement without complications. RT-PCR positivity in conjunctiva demonstrated the presence of the Monkeypox virus, suggesting that ocular-mediated transmission could be plausible. Ophthalmologists should be aware of this ophthalmic manifestation.
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