| Author | Moraes, Marcia Terezinha Baroni de | |
| Author | Silva, Mauro França da | |
| Author | Pimenta, Yan Cardoso | |
| Author | Cantelli, Carina Pacheco | |
| Author | Assis, Rosane Maria Santos de | |
| Author | Fialho, Alexandre Madi | |
| Author | Bueno, Marina Galvão | |
| Author | Olivares, Alberto Ignácio Olivares | |
| Author | Svensson, Lennart | |
| Author | Leite, José Paulo Gagliardi | |
| Author | Nordgren, Johan | |
| Access date | 2024-04-15T13:15:18Z | |
| Available date | 2024-04-15T13:15:18Z | |
| Document date | 2023 | |
| Citation | MORAES, Marcia Terezinha Baroni de et al. G6P[8] Rotavirus a Possessing a Wa-like VP3 Gene from a Child with Acute Gastroenteritis Living in the Northwest Amazon Region. Patógenos, v. 12, n. 956, p. 1-12, 2023. | en_US |
| ISSN | 2076-0817 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/63496 | |
| Language | eng | en_US |
| Publisher | MDPI | en_US |
| Rights | open access | |
| Title | G6P[8] Rotavirus a Possessing a Wa-like VP3 Gene from a Child with Acute Gastroenteritis Living in the Northwest Amazon Region | en_US |
| Type | Article | |
| DOI | 10.3390/patógenos12070956 | |
| Abstract | The introduction of rotavirus A (RVA) vaccines has considerably reduced the RVAassociated mortality among children under 5 years of age worldwide. The ability of RVA to reassort gives rise to different combinations of surface proteins G (glycoprotein, VP7) and P (protease sensitive, VP4) RVA types infecting children. During the epidemiological surveillance of RVA in the Northwest Amazon region, an unusual rotavirus genotype G6P[8] was detected in feces of a 2-year-old child with acute gastroenteritis (AGE) that had been vaccinated with one dose of Rotarix® (RV1). The G6P[8] sample had a DS-1-like constellation with a Wa-like VP3 gene mono-reassortment similar to equine-like G3P[8] that has been frequently detected in Brazil previously. The results presented here reinforce the evolutionary dynamics of RVA and the importance of constant molecular surveillance. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Programa de Pós-Graduação em Medicina Tropical. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Programa de Pós-Graduação em Medicina Tropical. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos (Biomanguinhos). Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Programa de Pós-Graduação em Medicina Tropical. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Secretaria Estadual de Saúde de Roraima. Boa Vista, RR, Brasil / Universidade Estadual de Roraima. Faculdade de Medicina. Boa Vista, RR, Brasil. | en_US |
| Affilliation | Linköping University. Department of Clinical and Experimental Medicine. Division of Molecular Virology. Linköping, Sweden / Kalolinska Institutet. Department of Medicine. Stockholm, Sweden. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Linköping University. Department of Clinical and Experimental Medicine. Division of Molecular Virology. Linköping, Sweden. | en_US |
| Subject | Rotavirus | en_US |
| Subject | Acute gastroenteritis | en_US |
| Subject | Amazon region | en_US |
