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2026
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ZIKA VIRUS: ADVANCING A PRIORITY RESEARCH AGENDA FOR PREPAREDNESS AND RESPONSE
Lackritz, Eve M et al. | Date Issued: 2025
Author
Lackritz, Eve M
Ng, Lee Ching
Marques, Ernesto T. A.
Rabe, Ingrid B.
Bourne, Nigel
Staples, J. Erin
Méndez-Rico, Jairo A.
Harris, Eva
Brault, Aaron C.
Ko, Albert I.
Beasley, David W. C.
Leighton, Tabitha
Wilder-Smith, Annelies
Ostrowsky, Julia T.
Mehr, Angela J.
Ulrich, Angela K.
Velayudhan, Raman
Golding, Josephine P.
Fay, Petra C.
Cehovin, Ana
Moua, Nicolina M.
Moore, Kristine A.
Osterholm, Michael T.
Barrett, Alan D. T.
Affilliation
Center for Infectious Disease Research and Policy. University of Minnesota. Minneapolis, MN, USA.
National Environment Agency, Environmental Health Institute. Saw Swee Hock School of Public Health. National University of Singapore. Singapore.
Department of Infectious Diseases and Microbiology. School of Public Health. University of Pittsburgh. Pittsburgh, PA, USA / Fundação Oswaldo Cruz. Departamento de Virologia e Terapêutica Experimental. Recife, PE, Brasil.
World Health Organization. Geneva, Switzerland.
Department of Pediatrics. University of Texas Medical Branch. Galveston, TX, USA / Sealy Institute for Vaccine Sciences. University of Texas Medical Branch. Galveston, TX, USA.
Division of Vector-Borne Diseases. Centers for Disease Control and Prevention. Fort Collins, CO, USA.
Pan American Health Organization. WHO Region of the Americas. Washington, DC, USA.
Division of Infectious Diseases and Vaccinology. School of Public Health. University of California Berkeley. Berkeley, CA, USA.
Division of Vector-Borne Diseases. Centers for Disease Control and Prevention. Fort Collins, CO, USA.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Department of Epidemiology of Microbial Diseases. Yale School of Public Health. New Haven, CT, USA / Ministério da Saúde. Salvador, BA, Brasil.
Sealy Institute for Vaccine Sciences. University of Texas Medical Branch. Galveston, TX, USA / Department of Microbiology and Immunology. University of Texas Medical Branch. Galveston, TX, USA.
Center for Infectious Disease Research and Policy. University of Minnesota. Minneapolis, MN, USA.
World Health Organization. Geneva, Switzerland.
Center for Infectious Disease Research and Policy. University of Minnesota. Minneapolis, MN, USA.
Center for Infectious Disease Research and Policy. University of Minnesota. Minneapolis, MN, USA.
Center for Infectious Disease Research and Policy. University of Minnesota. Minneapolis, MN, USA.
World Health Organization. Geneva, Switzerland.
Infectious Disease Strategic Programme. Wellcome Trust. London, UK.
Infectious Disease Strategic Programme. Wellcome Trust. London, UK.
Infectious Disease Strategic Programme. Wellcome Trust. London, UK.
Center for Infectious Disease Research and Policy. University of Minnesota. Minneapolis, MN, USA.
Center for Infectious Disease Research and Policy. University of Minnesota. Minneapolis, MN, USA.
Center for Infectious Disease Research and Policy. University of Minnesota. Minneapolis, MN, USA.
Sealy Institute for Vaccine Sciences. University of Texas Medical Branch. Galveston, TX, USA / Center for Infectious Disease Research and Policy. University of Minnesota. Minneapolis, MN, USA.
Abstract
The 2015–16 Zika virus epidemic emerged in the Americas and rapidly spread throughout the region and beyond, showing the epidemic potential of this mosquito-borne Orthoflavivirus and its capacity to cause severe congenital malformations and neurological sequelae. WHO declared the Zika virus epidemic a public health emergency of international concern in 2016. Despite this declaration, there are no licensed Zika virus vaccines, therapeutics, or diagnostic tests appropriate for routine antenatal screening. To address this absence of essential tools to detect and mitigate the threat of future Zika virus outbreaks, a group of global experts developed a priority agenda for Zika virus research and development. This Series paper summarises crucial challenges and knowledge gaps and outlines a comprehensive strategy to advance research, surveillance, global capacity, policy, and investment for Zika virus preparedness and response.
Keywords
Zika virus
Pesquisa prioritária
 
Publisher
Elsevier
Citation
LACKRITZ, Eve M et al. Zika virus: advancing a priority research agenda for preparedness and response. The Lancet Infectious Diseases, p. 1-12, 2025.
DOI
10.1016/S1473-3099(24)00794-1
ISSN
1474-4457