| Author | Desiderio, Elisangela Oliveria | |
| Author | Martins Júnior, Valdo Soares | |
| Author | Caldeira, Alisson Samuel Portes | |
| Author | Alves, Tânia Maria de Almeida | |
| Author | Cruz, Juliana Pimenta | |
| Author | Vieira, Thallyta Maria | |
| Author | Vasconcelos, Viviane Oliveira | |
| Author | Duarte, Eduardo Robson | |
| Access date | 2025-04-24T17:01:00Z | |
| Available date | 2025-04-24T17:01:00Z | |
| Document date | 2025 | |
| Citation | DESIDERIO, Elisangela Oliveria et al. Larvicidal activity of Magonia pubescens A. St.-Hil. (Sapindaceae) seed and leaf extract on Aedes aegypti. Nat Prod Res., v. 6, 1-9, 2025. | en_US |
| ISSN | 1478-6427 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/69864 | |
| Language | eng | en_US |
| Publisher | Taylor & Francis Health Sciences | en_US |
| Rights | restricted access | en_US |
| Title | Larvicidal activity of Magonia pubescens A. St.-Hil.(Sapindaceae) seed and leaf extract on Aedes aegypti | en_US |
| Type | Article | en_US |
| Abstract | Plant-derived compound emerges as alternatives to integrated control of Aedes aegypti, the main transmitter of Chikungunya, Dengue, Zika virus. The effects of Magonia pubescens A. St.-Hill extracts on Ae. aegypti larval development were assessed. Four in vitro assays analysed the insecticidal potential (% larval mortality) of aqueous and ethanolic (EE) extracts of leaves and seeds. The extracts were analysed using UHPLC-MS/MS. By comparing to data from three databases, 12 compounds from different classes were identified in the EE, including coumarins, phenolic acids, polyphenols, and flavonoids. The EE from the leaves was the most effective, with an LC90 of 0.262 mg/mL. Morphological alterations were observed in larvae exposed to the extracts, showing epithelial walls with extravasation of intestinal contents. These findings highlight the effectiveness of M. pubescens extract as a bioinsecticidal agent against Ae. aegypti larvae. | en_US |
| Affilliation | Universidade Estadual de Montes Claros. Pós graduação em Botânica Aplicada. Montes Claros, MG, Brasil. | en_US |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Agrárias. Pós-graduação em Produção Animal. Montes Claros, MG, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil. | en_US |
| Affilliation | Universidade Estadual de Montes Claros. Montes Claros, MG, Brasil. | en_US |
| Affilliation | Universidade Estadual de Montes Claros. Montes Claros, MG, Brasil. | en_US |
| Affilliation | Universidade Estadual de Montes Claros. Pós graduação em Botânica Aplicada. Montes Claros, MG, Brasil. | en_US |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Agrárias. Pós-graduação em Produção Animal. Montes Claros, MG, Brasil. | en_US |
| Subject | Aedes aegypti | en_US |
| Subject | Cerrado | en_US |
| Subject | Magonia pubescens | en_US |
| Subject | UHPLC-MS/MS | en_US |
| Subject | bioinsecticide | en_US |
| Embargo date | 3100-12-31 | |
