Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/7106
Title: Resistance to Schistosoma mansoni by transplantation of APO Biomphalaria tenagophila
Authors: Barbosa, Luciene
Caldeira, Roberta Lima
Carvalho, Omar dos Santos
Vidigal, Teofania Heloisa Dutra Amorim
Passos, Liana konovaloff Jannotti
Coelho, Paulo Marcos Zach
Affilliation: Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Parasitologia. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Esquistossomose. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Esquistossomose. Belo Horizonte, MG, Brazil
Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Zoologia. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Seção de Moluscário. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Esquistossomose. Belo Horizonte, MG, Brazil/Santa Casa de Misericórdia. Belo Horizonte, MG, Brazil
Abstract: Transplantation of the haematopoietic organ from Biompha-laria tenagophila (Taim strain, RS, Brazil), resistant to Schistosoma mansoni, to a highly susceptible strain (Cabo Frio, RJ, Brazil) of the same species, showed in the recipient snails resistance against the trematode, when a successful transplant occurred. The success of transplantation could be confirmed by a typical molecular marker of the Taim strain in haemocytes of the recipients (350 bp detected by PCR-RFLP). The recipient snails which did not present the donor marker in haemocytes (unsuccessful transplantation) were infected with the parasite. The use of an atoxic modelling clay for closing the hole in the transplantation site reduced significantly the mortality caused by bleeding after transplantation procedures.
Keywords: Biomphalaria tenagophila
hematopoietic organ (APO)
resistance
Schistosoma mansoni
transplantation
Issue Date: 2006
Publisher: Blackwell Scientific Publications
Citation: BARBOSA L. et al. Resistance to Schistosoma mansoni by transplantation of APO Biomphalaria tenagophila. Parasite Immunol. 2006 May;28(5):209-12.
ISSN: 0141-9838
Copyright: restricted access
Appears in Collections:MG - IRR - Artigos de Periódicos

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