| Author | Fleming, Fiona M. | |
| Author | Brooker, Simon | |
| Author | Geiger, Stefan Michael | |
| Author | Caldas, Iramaya Rodrigues | |
| Author | Oliveira, Rodrigo Correa de | |
| Author | Hotez, Peter J. | |
| Author | Bethony, Jeffrey Michael | |
| Access date | 2013-10-11T14:17:18Z | |
| Available date | 2013-10-11T14:17:18Z | |
| Document date | 2006 | |
| Citation | FLEMING, Fiona M. et al. Synergistic associations between hookworm and other helminth species in a rural community in Brazil. Tropical Medicine & International Health. 2006; 11(1): 56-64 | pt_BR |
| ISSN | 1365-3156 | |
| URI | https://www.arca.fiocruz.br/handle/icict/7127 | |
| Language | eng | pt_BR |
| Publisher | Blackwell Publishing | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Synergistic associations between hookworm and other helminth species in a rural community in BrazilSynergistic associations between hookworm and other helminth species in a rural community in Brazil | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1111/j.1365-3156.2005.01541.x | |
| Abstract | Objective To identify possible synergistic associations of hookworm and other helminths.
Method Cross-sectional survey of all households within 10 km2 of Americaninhas, a rural community in Minas Gerais, Brazil. We determined the prevalence and intensity of single and multiple helminth species infection in an age-stratified sample of 1332 individuals from 335 households.
Results Hookworm was the most prevalent helminth infection (68.2%), followed by Ascaris lumbricoides (48.8%) and Schistosoma mansoni (45.3%). Overall, 60.6% of individuals harboured mixed helminth infections. Multivariate analysis indicated significant positive associations for co-infection with hookworm and S. mansoni and for co-infection with hookworm and A. lumbricoides. Co-infections with hookworm and A. lumbricoides resulted in higher egg counts for both, suggesting a synergistic relationship between these species, although, we found important age differences in this relationship. However, the intensity of S. mansoni or A. lumbricoides co-infection did not differ from that of mono-infection.
Conclusion These results have implications for the epidemiology, immunology and control of multiple helminth infections. More research is needed to examine the rates of re-infection and immune responses after chemotherapy, and to what extent the effects of polyparasitism are altered by chemotherapy. | pt_BR |
| Affilliation | London School of Hygiene and Tropical Medicine. Department of Infectious and Tropical Diseases. London, UK/ Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | London School of Hygiene and Tropical Medicine. Department of Infectious and Tropical Diseases. London, UK | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, Brazil/The George Washington University. Department of Microbiology and Tropical Medicine Washington DC, USA | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | George Washington University. Department of Microbiology and Tropical Medicine Washington DC, USA | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, Brazil/George Washington University. Department of Microbiology and Tropical Medicine Washington DC, USA | pt_BR |
| Subject | hookworm | pt_BR |
| Subject | Ascaris lumbricoides | pt_BR |
| Subject | Schistosoma mansoni | pt_BR |
| Subject | epidemiology | pt_BR |
| Subject | polyparasitism | pt_BR |
| Subject | Brazil | pt_BR |
