| Author | Kajdacsi, Brittney | |
| Author | Costa, Federico | |
| Author | Hyseni, Chaz | |
| Author | Porter, Fleur Helena | |
| Author | Brown, Julia | |
| Author | Rodrigues, Gorete | |
| Author | Farias, Helena | |
| Author | Reis, Mitermayer Galvão dos | |
| Author | Childs, James E | |
| Author | Ko, Albert Icksang | |
| Author | Caccone, Adalgisa | |
| Access date | 2014-04-02T16:32:28Z | |
| Available date | 2014-04-02T16:32:28Z | |
| Document date | 2013 | |
| Citation | KAJDACSI B. et al. Urban population genetics of slum-dwelling rats (Rattus norvegicus) in Salvador, Brazil. Molecular Ecology, v. 22, n. 20, p. 5056–5070, 2013. | pt_BR |
| ISSN | 1365-294X | |
| URI | https://www.arca.fiocruz.br/handle/icict/7484 | |
| Language | eng | pt_BR |
| Publisher | Blackwell Scientific Publications | pt_BR |
| Rights | open access | pt_BR |
| Title | Urban population genetics of slum-dwelling rats (Rattus norvegicus) in Salvador, Brazil. | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1111/mec.12455 | |
| Abstract | Throughout the developing world, urban centres with sprawling slum settlements are rapidly expanding and invading previously forested ecosystems. Slum communities are characterized by untended refuse, open sewers and overgrown vegetation, which promote rodent infestation. Norway rats (Rattus norvegicus) are reservoirs for epidemic transmission of many zoonotic pathogens of public health importance. Understanding the population ecology of R. norvegicus is essential to formulate effective rodent control strategies, as this knowledge aids estimation of the temporal stability and spatial connectivity of populations. We screened for genetic variation, characterized the population genetic structure and evaluated the extent and patterns of gene flow in the urban landscape using 17 microsatellite loci in 146 rats from nine sites in the city of Salvador, Brazil. These sites were divided between three neighbourhoods within the city spaced an average of 2.7 km apart. Surprisingly, we detected very little relatedness among animals trapped at the same site and found high levels of genetic diversity, as well as structuring across small geographical distances. Most F(ST) comparisons among sites were statistically significant, including sites <400 m apart. Bayesian analyses grouped the samples in three genetic clusters, each associated with distinct sampling sites from different neighbourhoods or valleys within neighbourhoods. These data indicate the existence of complex genetic structure in R. norvegicus in Salvador, linked to the heterogeneous urban landscape. Future rodent control measures need to take into account the spatial and temporal linkage of rat populations in Salvador, as revealed by genetic data, to develop informed eradication strategies. | pt_BR |
| Affilliation | Yale University. Department of Ecology and Evolutionary Biology. New Haven, USA | pt_BR |
| Affilliation | Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Yale University. Department of Ecology and Evolutionary Biology. New Haven, USA | pt_BR |
| Affilliation | Yale University. Department of Ecology and Evolutionary Biology. New Haven, USA | pt_BR |
| Affilliation | Yale University. Department of Ecology and Evolutionary Biology. New Haven, USA | pt_BR |
| Affilliation | Ministério da Saúde. Secretaria Municipal de Sa ude. Centro de Controle de Zoonoses. Salvador, BA, Brasil | pt_BR |
| Affilliation | Ministério da Saúde. Secretaria Municipal de Sa ude. Centro de Controle de Zoonoses. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA | pt_BR |
| Affilliation | Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Yale University. Department of Ecology and Evolutionary Biology. New Haven, USA | pt_BR |
| Subject | Population genetics | pt_BR |
| Subject | Rattus norvegicus | pt_BR |
| Subject | Rodent control | pt_BR |
| Subject | Urban ecology | pt_BR |
| DeCS | Variação Genética | pt_BR |
| DeCS | Genética Populacional/métodos | pt_BR |
| DeCS | Áreas de Pobreza | pt_BR |
| DeCS | Ratos/genética | pt_BR |
| DeCS | Animais | pt_BR |
| DeCS | Teorema de Bayes | pt_BR |
| DeCS | Brasil | pt_BR |
| DeCS | Vetores de Doenças | pt_BR |
| DeCS | Fluxo Gênico | pt_BR |
| DeCS | Repetições de Microssatélites | pt_BR |
| DeCS | Controle de Pragas | pt_BR |
| DeCS | Densidade Demográfica | pt_BR |
| xmlui.metadata.dc.subject.ods | 11 Cidades e comunidades sustentáveis | |
