Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/7484
Title: Urban population genetics of slum-dwelling rats (Rattus norvegicus) in Salvador, Brazil.
Authors: Kajdacsi, Brittney
Costa, Federico
Hyseni, Chaz
Porter, Fleur Helena
Brown, Julia
Rodrigues, Gorete
Farias, Helena
Reis, Mitermayer Galvão dos
Childs, James E
Ko, Albert Icksang
Caccone, Adalgisa
Affilliation: Yale University. Department of Ecology and Evolutionary Biology. New Haven, USA
Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Yale University. Department of Ecology and Evolutionary Biology. New Haven, USA
Yale University. Department of Ecology and Evolutionary Biology. New Haven, USA
Yale University. Department of Ecology and Evolutionary Biology. New Haven, USA
Ministério da Saúde. Secretaria Municipal de Sa ude. Centro de Controle de Zoonoses. Salvador, BA, Brasil
Ministério da Saúde. Secretaria Municipal de Sa ude. Centro de Controle de Zoonoses. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA
Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Yale University. Department of Ecology and Evolutionary Biology. New Haven, USA
Abstract: Throughout the developing world, urban centres with sprawling slum settlements are rapidly expanding and invading previously forested ecosystems. Slum communities are characterized by untended refuse, open sewers and overgrown vegetation, which promote rodent infestation. Norway rats (Rattus norvegicus) are reservoirs for epidemic transmission of many zoonotic pathogens of public health importance. Understanding the population ecology of R. norvegicus is essential to formulate effective rodent control strategies, as this knowledge aids estimation of the temporal stability and spatial connectivity of populations. We screened for genetic variation, characterized the population genetic structure and evaluated the extent and patterns of gene flow in the urban landscape using 17 microsatellite loci in 146 rats from nine sites in the city of Salvador, Brazil. These sites were divided between three neighbourhoods within the city spaced an average of 2.7 km apart. Surprisingly, we detected very little relatedness among animals trapped at the same site and found high levels of genetic diversity, as well as structuring across small geographical distances. Most F(ST) comparisons among sites were statistically significant, including sites <400 m apart. Bayesian analyses grouped the samples in three genetic clusters, each associated with distinct sampling sites from different neighbourhoods or valleys within neighbourhoods. These data indicate the existence of complex genetic structure in R. norvegicus in Salvador, linked to the heterogeneous urban landscape. Future rodent control measures need to take into account the spatial and temporal linkage of rat populations in Salvador, as revealed by genetic data, to develop informed eradication strategies.
Keywords: Population genetics
Rattus norvegicus
Rodent control
Urban ecology
DeCS: Variação Genética
Genética Populacional/métodos
Áreas de Pobreza
Ratos/genética
Animais
Teorema de Bayes
Brasil
Vetores de Doenças
Fluxo Gênico
Repetições de Microssatélites
Controle de Pragas
Densidade Demográfica
Issue Date: 2013
Publisher: Blackwell Scientific Publications
Citation: KAJDACSI B. et al. Urban population genetics of slum-dwelling rats (Rattus norvegicus) in Salvador, Brazil. Molecular Ecology, v. 22, n. 20, p. 5056–5070, 2013.
DOI: 10.1111/mec.12455
ISSN: 1365-294X
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

Files in This Item:
File Description SizeFormat 
Kajdacsi B Urban populations....pdf1.4 MBAdobe PDFThumbnail
View/Open


FacebookTwitterDeliciousLinkedInGoogle BookmarksBibTex Format mendeley Endnote DiggMySpace

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.