Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/7565
Title: Population-based case-control investigation of risk factors for leptospirosis during an urban epidemic.
Authors: Sarkar, Urmimala
Nascimento, Simone F
Barbosa, Rosan
Martins, Ridalva
Nuevo, Hector
Kalafanos, Ippolytos
Grunstein, Itamar
Flannery, Brendan
Dias, Juarez Pereira
Riley, Lee Woodland
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
Affilliation: School of Public Health. University of California. Berkeley, CA
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
School of Public Health. University of California. Berkeley, CA
School of Public Health. University of California. Berkeley, CA
School of Public Health. University of California. Berkeley, CA
Secretaria da Saúde do Estado da Bahia. Departamento de Vigilância Epidemiológica. Salvador, BA, Brasil
School of Public Health. University of California. Berkeley, CA
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Division of International Medicine and Infectious Diseases. Weill Medical College of Cornell University. New York, NY
Abstract: Between March and October 2000, 157 suspected cases of leptospirosis hospitalized with complications of Weil’s syndrome and a mortality of 8% were identified in Salvador, Brazil. We conducted a population-based casecontrol study to identify risk factors for acquisition of leptospirosis in neighborhoods with high endemicity during the rainy season-associated urban epidemic. Sixty-six (65%) of 101 laboratory-confirmed cases and 125 age and sex-matched healthy neighborhood controls were interviewed. Residence in proximity to an open sewer (matched odds ratio [OR] 5.15, 95% confidence interval [CI] 1.80–14.74), peri-domiciliary sighting of rats (OR 4.49, 95% CI 1.57–12.83), sighting groups of five or more rats (OR 3.90, 95% CI 1.35–11.27), and workplace exposure to contaminated environmental sources (OR 3.71, 95% CI 1.35–10.17) were found to be independent risk factors for acquiring disease. Some of these risk factors are amenable to focused interventions, which include provision of closed drainage systems for sewage and reduction of rodent populations in the peri-domicilary environment. Environmental control of transmission may help to greatly reduce the incidence of severe leptospirosis.
DeCS: Leptospirose/epidemiologia
População Urbana/estatística & dados numéricos
Adolescente
Adulto
Animais
Brasil/epidemiologia
Estudos de Casos e Controles
Surtos de Doenças
Reservatórios de Doenças
Emprego
Feminino
Humanos
Masculino
Ratos
Valores de Referência
Fatores de Risco
Saneamento/normas
Estações do Ano
Issue Date: 2002
Publisher: American Society of Tropical Medicine and Hygiene
Citation: SARKAR, U. et al.Population-based case-control investigation of risk factors for leptospirosis during an urban epidemic. American Journal of Tropical Medicine and Hygiene, v. 66, n. 5, p. 605-610, 2002.
ISSN: 0002-9637
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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