Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/7794
Title: Puerperal brain cryptococcoma in an HIV-negative woman
Authors: Hagan, José Edward
Dias, Jesângeli Sousa
Villasbôas Bisneto, José Caetano
Falcão, Melissa Barreto
Ko, Albert Icksang
Ribeiro, Guilherme de Sousa
Affilliation: Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, CT, USA / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Hospital Couto Maia. Secretaria de Saúde do Estado da Bahia. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Hospital Couto Maia. Secretaria de Saúde do Estado da Bahia. Salvador, BA, Brasil
Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, CT, USA / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil
Abstract: Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus fl ucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV-negative woman diagnosed with a large cryptococcoma in the immediate postpartum period. The lesion was not resected, and due to amphotericin B intolerance, she received an extended course of fl uconazole monotherapy. There was no disease recurrence during the 4 years of follow-up. The abrupt onset of her symptoms following delivery suggests that she developed a postpartum immune reconstitution syndrome. This case also demonstrates that in specifi c situations fl uconazole monotherapy can be attempted in immunocompetent patients with cryptococcoma
Keywords: Cryptococcus
Immune reconstitution inflammatory syndrome
Treatment
Issue Date: 2014
Publisher: Sociedade Brasileira de Medicina Tropical
Citation: HAGAN, J. E. et al. Puerperal brain cryptococcoma in an HIV-negative woman. Revista da Sociedade Brasileira de Medicina Tropical, v. 47, n. 2, p. 254-256, 2014.
DOI: 10.1590/0037-8682-0215-2013
ISSN: 0037-8682
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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