Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/7814
Title: Fatty liver disease in severe obese patients: diagnostic value of abdominal ultrasound
Authors: Almeida, Alessandro de Moura
Cotrim, Helma Pinchemel
Barbosa, Daniel Batista Valente
Athayde, Luciana Gordilho Matteoni de
Santos, Adimeia Souza
Bitencourt, Almir Galvão Vieira
Freitas, Luiz Antonio Rodrigues de
Rios, Adriano
Alves, Erivaldo
Affilliation: Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil.
Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil.
Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil.
Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil.
Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil.
Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil.
Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil.
Núcleo de Cirurgia da Obesidade. Salvador, BA, Brasil.
Núcleo de Cirurgia da Obesidade. Salvador, BA, Brasil.
Abstract: AIM: To evaluate the sensitivity and specificity of abdominal ultrasound (US) for the diagnosis of hepatic steatosis in severe obese subjects and its relation to histological grade of steatosis. METHODS: A consecutive series of obese patients, who underwent bariatric surgery from October 2004 to May 2005, was selected. Ultrasonography was performed in all patients as part of routine preoperative time and an intraoperative wedge biopsy was obtained at the beginning of the bariatric surgery. The US and histological findings of steatosis were compared, considering histology as the gold standard. RESULTS: The study included 105 patients. The mean age was 37.2+/-10.6 years and 75.2% were female. The histological prevalence of steatosis was 89.5%. The sensitivity and specificity of US in the diagnosis of hepatic steatosis were, respectively, 64.9% (95% CI: 54.9-74.3) and 90.9% (95% CI: 57.1-99.5). The positive predictive value and negative predictive value were, respectively, 98.4% (95% CI: 90.2-99.9) and 23.3% (95% CI: 12.3-39.0). The presence of steatosis on US was associated to advanced grades of steatosis on histology (P=0.016). CONCLUSION: Preoperative abdominal US in our series has not shown to be an accurate method for the diagnosis of hepatic steatosis in severe obese patients. Until another non-invasive method demonstrates better sensitivity and specificity values, histological evaluation may be recommended to these patients undergoing bariatric surgery.
Keywords: Bariatric surgery
Obesity
Hepatic steatosis
Abdominal ultrasound diagnosis
Fatty liver
DeCS: Fígado Gorduroso/complicações
Fígado Gorduroso/ultrassonografia
Obesidade Mórbida/complicações
Obesidade Mórbida/complicações
Adulto
Cirurgia Bariátrica
Biópsia
Feminino
Humanos
Fígado/patologia
Fígado/ultrassonografia
Masculino
Meia-Idade
Obesidade Mórbida/cirurgia
Reprodutibilidade dos Testes
Prevalência
Sensibilidade e Especificidade
Índice de Gravidade de Doença
Issue Date: 2008
Publisher: Baishideng Publishing Group Co. Limited
Citation: ALMEIDA, Alessandro de Moura et al. Fatty liver disease in severe obese patients: diagnostic value of abdominal ultrasound. World Journal of Gastroenterology, v. 14, n. 9, p. 1415-1418, 2008.
DOI: 10.3748/wjg.14.1415
ISSN: 1007-9327
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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