Author | Dourado, Inês | |
Author | Alcantara, Luiz Carlos Júnior | |
Author | Barreto, Maurício Lima | |
Author | Teixeira, Maria da Glória | |
Author | Castro Filho, Bernardo Galvão | |
Access date | 2014-08-06T13:19:12Z | |
Available date | 2014-08-06T13:19:12Z | |
Document date | 2003 | |
Citation | DOURADO, I. et al. HTLV-I in the general population of Salvador, Brazil: a city with African ethnic and sociodemographic characteristics. Journal of Acquired Immune Deficiency Syndromes, v. 34, n. 5, p. 527-531, 2003. | pt_BR |
ISSN | 1525-4135 | |
URI | https://www.arca.fiocruz.br/handle/icict/8136 | |
Language | eng | pt_BR |
Publisher | Lippincott Williams & Wilkins | pt_BR |
Rights | open access | pt_BR |
Title | HTLV-I in the general population of Salvador, Brazil: a city with African ethnic and sociodemographic characteristics. | pt_BR |
Type | Article | pt_BR |
Abstract | The city of Salvador has the highest prevalence of
HTLV-I among blood donors in Brazil. To study the prevalence of
HTLV-I among the general population of Salvador, 30 “sentinel surveillance
areas” were selected for the investigation of various infectious
diseases, and 1385 individuals within these areas were surveyed
according to a simple random sample procedure. ELISA was used to
screen plasma samples for antibodies to HTLV-I, and the positive
samples were tested by a confirmatory assay (Western blotting). The
overall prevalence of HTLV-I was 1.76% (23/1385). Infection rates
were 1.2% for males and 2.0% for females. Specific prevalence demonstrated
an increasing linear trend with age. No one younger than 13
years of age was infected. Multivariate analysis estimated adjusted
odds ratios for the association of HTLV-I with age of 9.7 (3.3; 30.4)
for females and 12.3 (1.47; 103.1) for males. Less education and income
might be associated with HTLV-I infection in females. Phylogenetic
analysis of the long terminal repeat fragments showed that
most of the samples belonged to the Latin American cluster of the
Transcontinental subgroup (Cosmopolitan subtype). For the entire
city of Salvador, it is estimated that ∼40,000 individuals are infected
with HTLV-I. Our results suggest multiple post-Colombian introductions
of African HTLV-Ia strains in Salvador. | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Fundação Bahiana para Desenvolvimento das Ciências. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Fundação Bahiana para Desenvolvimento das Ciências. Salvador, BA, Brasil | pt_BR |
DeCS | Infecções por HTLV-I/epidemiologia | pt_BR |
DeCS | Adolescente | pt_BR |
DeCS | Adulto | pt_BR |
DeCS | África/etnologia | pt_BR |
DeCS | Doadores de Sangue | pt_BR |
DeCS | Brasil/epidemiologia | pt_BR |
DeCS | Criança | pt_BR |
DeCS | Demografia | pt_BR |
DeCS | Escolaridade | pt_BR |
DeCS | Ensaio de Imunoadsorção Enzimática | pt_BR |
DeCS | Feminino | pt_BR |
DeCS | Soroprevalência de HIV | pt_BR |
DeCS | Anticorpos Anti-HTLV-I/sangue | pt_BR |
DeCS | Infecções por HTLV-I/diagnóstico | pt_BR |
DeCS | Humanos | pt_BR |
DeCS | Renda | pt_BR |
DeCS | Masculino | pt_BR |
DeCS | Meia-Idade | pt_BR |
DeCS | Prevalência | pt_BR |
DeCS | Fatores Socioeconômicos | pt_BR |
DeCS | População Urbana | pt_BR |