Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/8152
Title: Human T lymphotropic virus type I (HTLV-I) infection in neurological patients in Salvador, Bahia, Brazil.
Authors: Gomes, Irênio
Melo, Ailton
Proietti, Fernando Augusto
Carvalho, Otavio Augusto Moreno
Loures, Luiz Antonio M
Dazza, Marie Christine
Said, Gerard
Larouzé, Bernard
Castro Filho, Bernardo Galvão
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, Brasil
Universidade Federal da Bahia. Departamento de Neuro-Psiquiatria. Salvador, BA, Brasil
Universidade Federal de Minas Gerais. Departamento de Medicina Preventiva e Social. Belo Horizonte, MG, Brasil
Fundação José Silveira. Laboratório de Líquor. Salvador, BA, Brasil
Ministry of Health. National Program of STD/AIDS. Brasilia, DF, Brasil
Institut de Medecine et d’Epidemiologie Tropicales. Faculté Xavier Bichat. Paris, France
Hôpital du Kremlin-Bicêtre. Service de Neurologie. Kremlin Bicêtre, Paris, France
Institut de Medecine et d’Epidemiologie Tropicales. Faculté Xavier Bichat. Paris, France
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, Brasil
Abstract: HTLV-I infection represents a major health concern in endemic areas throughout the world, such as Salvador, the main city of Bahia State, with socio-demographic characteristics similar to sub-Saharan African cities, located in the Northeast of Brazil. In order to provide an estimate of the frequency distribution, and range of neurological manifestations potentially related to HTLV-I infection in this city, we conducted a cross-sectional clinical-epidemiological study to determine the prevalence of this infection in patients with neurological diseases. Patients exhibiting vascular diseases, tumoral diseases or trauma were excluded. Over a period of 16 months, we studied 322 consecutive patients with chronic neurological diseases, who attended the neurological clinics of two major hospitals in Salvador. Overall, the prevalence of HTLV-I infection among the patients was 20.9% (67/320). However, the prevalence among the 104 patients with chronic myelopathy was 50.0% (52/104). It was observed that the major prevalence of HTLV-I was between the ages of 40 and 60 years with a female predominance. Our data indicate that, in Salvador city, HTLV-I is associated with chronic myelopathies or myeloneuropathies, which seem to be the only neurological diseases associated with HTLV-I.
Keywords: HTLV-I
Neurological diseases
TSP
HAM
Prevalence
South America
DeCS: Infecções por HTLV-I/epidemiologia
Doenças do Sistema Nervoso/epidemiologia
Adolescente
Adulto
Brasil/epidemiologia
Anticorpos Antibacterianos/análise
Estudos Transversais
Anticorpos Antideltaretrovirus/análise
Feminino
Anticorpos Anti-HIV/análise
Infecções por HTLV-I/líquido cefalorraquidiano
Infecções por HTLV-I/diagnóstico
Humanos
Masculino
Meia-Idade
Doenças do Sistema Nervoso/diagnóstico
Estudos Soroepidemiológicos
Treponema pallidum/imunologia
Issue Date: 1999
Publisher: Elsevier
Citation: GOMES, I. et al. Human T lymphotropic virus type I (HTLV-I) infection in neurological patients in Salvador, Bahia, Brazil. Journal of the Neurological Sciences, v. 165, n. 1, p. 84–89, 1999.
ISSN: 0022-510X
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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