Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/8773
Title: Double integration band of HTLV-1 in a young patient with infective dermatitis who developed an acute form of adult T-cell leukemia/lymphoma.
Authors: Oliveira, Pedro Dantas
Silva, Marcelo Magalhães
Argôlo, Juliana Moreira
Bittencourt, Achilea Candida Lisboa
Vallve, Maria de Lourdes Farre
Affilliation: Federal University of Bahia. Complexo Hospitalar Universitário Prof. Edgard Santos. Service of Dermatology. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Federal University of Bahia. Complexo Hospitalar Universitário Prof. Edgard Santos. Service of Pathology. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Abstract: Few cases of acute adult T-cell leukemia/lymphoma (ATL) have been diagnosed in young patients. This report is the first to describe a young girl with infective dermatitis associated with HTLV-1 that progressed to acute ATL with Southern blot hybridization and gamma-TCR-rearrangement revealing a monoclonal pattern with two copies of the provirus.
Keywords: HTLV-1
Adult T-cell leukemia/lymphoma
Infective dermatitis
Proviral integration
DeCS: Dermatite/patologia
Dermatite/virologia
Vírus 1 Linfotrópico T Humano/genética
Leucemia-Linfoma de Células T do Adulto/patologia
Integração Viral
Adolescente
Southern Blotting
Dermatite/complicações
Feminino
Rearranjo Gênico
Genes Codificadores da Cadeia gama de Receptores de Linfócitos T
Humanos
Leucemia-Linfoma de Células T do Adulto/complicações
Provirus/genética
Adulto Jovem
Issue Date: 2013
Publisher: Elsevier B.V
Citation: OLIVEIRA, P. D. et al. Double integration band of HTLV-1 in a young patient with infective dermatitis who developed an acute form of adult T-cell leukemia/lymphoma. Journal of Clinical Virology, v. 56, n. 2, p. 163-166, 2013.
DOI: dx.doi.org/10.1016/j.jcv.2012.10.010
ISSN: 1873-5967
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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