Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/8805
Title: Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil.
Authors: Oliveira, Dayse Cury de Almeida
Carvalho, Magda Oliveira Seixas
Nascimento, Valma Maria Lopes do
Villas-Bôas, Flávia Silva
Castro Filho, Bernardo Galvão
Gonçalves, Marilda de Souza
Affilliation: Instituto Brasileiro de Oftalmologia e Prevenção da Cegueira (IBOPC). Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Publica. Salvador, BA, Brasil
Universidade Federal da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação de Hematologia e Hemoterapia do Estado da Bahia (HEMOBA). Salvador, BA, Brasil
Instituto Brasileiro de Oftalmologia e Prevenção da Cegueira (IBOPC). Salvador, BA, Brasil
Escola Bahiana de Medicina e Saúde Publica. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Universidade Federal da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia do Sangue (INCT). Campinas, SP, Brasil
Abstract: tObjective: The aim of the present study was to characterize sickle cell disease retinopathyin children and teenagers from Bahia, the state in northeastern Brazil with the highestincidence and prevalence of sickle cell disease.Methods: A group of 51 sickle cell disease patients (36 hemoglobin SS and 15 hemoglobinSC) with ages ranging from 4 to 18 years was studied. Ophthalmological examinations wereperformed in all patients. Moreover, a fluorescein angiography was also performed in over10-year-old patients.Results: The most common ocular lesions were vascular tortuosity, which was found in nine(25%) hemoglobin SS patients, and black sunburst, in three (20%) hemoglobin SC patients.Peripheral arterial closure was observed in five (13.9%) hemoglobin SS patients and in three(13.3%) hemoglobin SC patients. Arteriovenous anastomoses were present in six (16.5%)hemoglobin SS patients and six (37.5%) hemoglobin SC patients. Neovascularization wasnot identified in any of the patients.Conclusions: This study supports the use of early ophthalmological examinations in youngsickle cell disease patients to prevent the progression of retinopathy to severe disease andfurther blindness.
Keywords: Sickle cell anemia
Disease SC
Retinopathy
Issue Date: 2014
Publisher: Elsevier Editora Ltda
Citation: OLIVEIRA, D. C. A. et al. Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil. Revista Brasileira de Hematologia e Hemoterapia, v. 36, n. 5, p. 340-344, 2014.
DOI: dx.doi.org/10.1016/j.bjhh.2014.07.012
ISSN: 1516-8484
Copyright: open access
Appears in Collections:IGM - Artigos de Periódicos

Files in This Item:
File Description SizeFormat 
Oliveira DCA Sickle cell....pdf732.7 kBAdobe PDFView/Open


FacebookTwitterDeliciousLinkedInGoogle BookmarksBibTex Format mendeley Endnote DiggMySpace

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.