Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/8923
Title: Keratocystic odontogenic tumour: an experience in the Northeast of Brazil.
Authors: Mello, Leonardo Araújo
Gurgel, Clarissa Araújo Silva
Ramos, Eduardo Antônio Gonçalves
Souza, Renata Oliveira de
Sales, Caroline Brandi Schlaepfer
Azevedo, Roberto Almeida de
Santos, Jean Nunes dos
Affilliation: Federal University of Bahia. School of Dentistry. Laboratory of Oral Surgical Pathology. Department of Oral Pathology. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil
Federal University of Bahia. School of Dentistry. 3Division of Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery. Salvador, BA, Brasil
Federal University of Bahia. School of Dentistry. Laboratory of Oral Surgical Pathology. Department of Oral Pathology. Salvador, BA, Brasil
Abstract: Keratocystic odontogenic tumours raise particular interest, because of their high recurrence rate and association with nevoid basal cell carcinoma syndrome. OBJECTIVE: To analyze the clinical and histopathological features of all cases diagnosed as keratocystic odontogenic tumour in a Brazilian population. METHODS: A total of 64 keratocystic odontogenic tumours, arising in forty-six patients, were evaluated using the following parameters: association with nevoid basal cell carcinoma syndrome, gender, age at first diagnosis, race, anatomical location, symptoms, radiographic features, history of recurrence, association with teeth, and treatment. RESULTS: Keratocystic odontogenic tumours were more frequent among women than men (1:0.84). The mean patient age was 31.5 years (SD: +/- 16.6). Ten tumours (16.4%) involved the maxilla and 51 (83.6%) the mandible. Swelling (n = 12; 46.1%), followed by pain and swelling (n = 4; 15.3%), were most common clinical manifestations. A unilocular radiotransparency with well-defined margins was the main radiographic finding (n = 29; 87.8%). A significant association was observed between the multilocular radiographic pattern and recurrence (p < 0.05, Fisher's Test). Sixty-one (95.3%) tumours were treated by surgical enucleation followed by bone curettage, and the recurrence rate was 13% (n = 6). This study showed that the keratocystic odontogenic tumours relapsed within a mean period of 25-36 months. CONCLUSION: Despite the results of this study being similar to previous reports found in the literature, it provides an important insight about keratocystic odontogenic tumours in a Brazilian population
DeCS: Doenças Mandibulares
Neoplasias Mandibulares
Doenças Maxilares
Cistos Odontogênicos
Tumores Odontogênicos
Adolescente
Adulto
Brasil
Criança
Humanos
Feminino
Doenças Mandibulares/radiografia
Masculino
Doenças Mandibulares/terapia
Neoplasias Mandibulares/radiografia
Doenças Maxilares/radiografia
Cistos Odontogênicos/radiografia
Tumores Odontogênicos/radiografia
Issue Date: 2011
Citation: MELLO, L. A. et al. Keratocystic odontogenic tumour: an experience in the Northeast of Brazil. Srpski arhiv za celokupno lekarstvo, v. 139, n. 5-6, p. 291-297, 2011.
ISSN: 0370-8179
10.2298/SARH1106291A
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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