Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/9055
Title: Rotavirus gastroenteritis in children in 4 regions in Brazil: a hospital-based surveillance study
Authors: Munford, Veridiana
Gilio, Alfredo Elias
Souza, Eloisa Correa de
Cardoso, Debora Morais
Paula Cardoso, Divina das Dores de
Borges, Ana Maria Tavares
Costa, Paulo Sergio Sucasas da
Melgac, Irene Angela Melo
Rosa, Humberto
Carvalho, Paulo Roberto Antonacci
Goldani, Marcelo Zubaran
Moreira Júnior, Edson Duarte
Santana, Ciria
El Khoury, Antoine
Ikedo, Fabio
Rácz, Maria Lucia
Affilliation: Institute of Biomedical Science. Virology Laboratories. Department of Microbiology.
University Hospital. University of São Paulo. Medical School. São Paulo, SP, Brasil
University Hospital. University of São Paulo. Medical School. São Paulo, SP, Brasil
University Hospital. University of São Paulo. Medical School. São Paulo, SP, Brasil
Institute of Tropical Pathology and Public Health. Department of Microbiology, Immunology, Parasitology, and Pathology.
Institute of Tropical Pathology and Public Health. Department of Microbiology, Immunology, Parasitology, and Pathology.
Federal University of Goias. Department of Pediatrics. Góias, GO, Brasil
State Health Secretary. Materno-Infantil Hospital. Goiás, GO, Brasil
Federal University of Rio Grande do Sul. Department of Pediatrics. Porto Alegre, RS, Brasil
Federal University of Rio Grande do Sul. Department of Pediatrics. Porto Alegre, RS, Brasil
Federal University of Rio Grande do Sul. Department of Pediatrics. Porto Alegre, RS, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Irma Dulce Foundation. Salvador, BA, Brasil
Global Outcomes Research, Merck. West Point, Pennsylvania
Medical Department. MSD Brazil. São Paulo, SP, Brasil
Institute of Biomedical Science. Virology Laboratories. Department of Microbiology.
Abstract: BACKGROUND: Rotavirus is a major cause of gastroenteritis in children. Knowledge of rotavirus genotypes is important for vaccination strategies. METHODS: During 2005-2006, rotavirus surveillance studies were conducted in São Paulo, Salvador, Goiânia, and Porto Alegre, Brazil. Stool samples were collected from children <5 years of age who had diarrhea and were screened by the Rotaclone Enzyme Immunoassay for the presence of rotavirus. Confirmed rotavirus-positive samples were characterized for P and G genotypes by reverse-transcriptase polymerase chain reaction. RESULTS: A total of 510 stool samples were collected. Of these, 221 (43.3%) were positive for rotavirus. Overall, G9 was the predominant G type, followed by G2, and G1; P[4] and P[8] were the predominant P types. The most frequent G/P genotype combination detected was G2P[4], followed by G9P[8], G9P[4], and G1P[8]. G2P[4] was the predominant type in Goiânia and Salvador; G9P[8] and G1P[8] were predominant in São Paulo and Porto Alegre, respectively. CONCLUSIONS: The prevalence, seasonality, and genotype distribution of rotavirus infection varied in different regions in Brazil. With immunization programs, continuous monitoring of rotavirus types is important to detect novel and emerging strains.
DeCS: Gastroenterite/epidemiologia
Infecções por Rotavirus/epidemiologia
Adolescente
Adulto
Brasil/epidemiologia
Crianças
Pré-Escolar
Genótipo
Humanos
Lactente
Recém-Nascido
Rotavirus/classificação
Infecções por Rotavirus/virologia
Estações do Ano
Issue Date: 2009
Publisher: Oxford University Press
Citation: MUNFORD, V. et al. Rotavirus gastroenteritis in children in 4 regions in Brazil: a hospital-based surveillance study. Journal of Infectious Diseases, v. 200, Suppl 1, p. S106-113, 2009.
DOI: 10.1086/605037
ISSN: 1537-6613
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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