Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/9531
Title: Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil
Authors: Silva, Fabiana de Oliveira Lara
Barata, Ricardo Andrade
Michalsky, Érika Monteiro
Ferreira, Eduardo de Castro
Lopes, Maria Olímpia Garcia
Pinheiro, Aimara da Costa
Dias, Consuelo Latorre Fortes
Dias, Edelberto Santos
Affilliation: Fundacao Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Laboratorio de Leishmanioses. Belo Horizonte, MG, Brazil
Universidade Federal dos Vales do Jequitinhonha e Mucuri. Departamento de Ciencias Biologicas. Laboratorio de Parasitologia. Diamantina, MG, Brazil
Fundacao Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Laboratorio de Leishmanioses. Belo Horizonte, MG, Brazil
Fundacao Oswaldo Cruz. MS, Brazil
Biodiversity Salvation. Belo Horizonte, MG, Brazil
Secretaria Municipal de Saude. Governador Valadares, MG, Brazil
Fundacao Ezequiel Dias. Diretoria de Pesquisa e Desenvolvimento. Laboratorio de Enzimologia Aplicada. Belo Horizonte, MG, Brazil
Fundacao Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Laboratorio de Leishmanioses. Belo Horizonte, MG, Brazil
Abstract: In the present study we surveyed the fauna of phlebotomine sand flies and small mammals in peridomestic areas from a Brazilian municipality where the American cutaneous leishmaniasis (ACL) is endemic. A total of 608 female phlebotomine sand flies were captured during nine months in 2009 and 2010. Seven different species were represented with 60% of them being Lutzomyia intermedia and Lu. whitmani, both incriminated vectors of ACL. Lu. longipalpis, a proven vector of visceral leishmaniasis (VL) was also captured at high proportion (12.8%). Genomic DNA analysis of 136 species-specific pools of female sand flies followed by molecular genotyping showed the presence of Leishmania infantum DNA in two pools of Lu. longipalpis. The same Leishmania species was found in one blood sample from Rattus norvegicus among 119 blood and tissue samples analysed. This is the first report of Le. infantum in R. norvegicus in the Americas and suggests a possible role for this rodent species in the zoonotic cycle of VL. Our study coincided with the reemergence of VL in Governador Valadares.
Keywords: Leishmania Infantum
Leishmania virus
Issue Date: 2014
Publisher: Hindawi Publishing Corporation
Citation: SILVA, Fabiana de Oliveira Lara et al. Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil. BioMed Research International Volume, 2014, Article ID 592986, 7 p.
DOI: 10.1155/2014/592986
ISSN: 2314-6141
Copyright: open access
Appears in Collections:MG - IRR - Artigos de Periódicos

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