| Author | Porto, Lia Pontes Arruda | |
| Author | Santos, Jean Nunes dos | |
| Author | Ramalho, Luciana Maria Pedreira | |
| Author | Figueiredo, Andreia Leal | |
| Author | Carneiro Júnior, Bráulio | |
| Author | Gurgel, Clarissa Araújo | |
| Author | Paiva, Katiúcia Batista Silva | |
| Author | Xavier, Flávia Caló Aquino | |
| Access date | 2018-03-27T17:25:16Z | |
| Available date | 2018-03-27T17:25:16Z | |
| Document date | 2016 | |
| Citation | PORTO, L. P. A. et al. E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors. Journal of Oral Pathology & Medicine, v. 45, p. 302–311, 2016. | pt_BR |
| ISSN | 0904-2512 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/25532 | |
| Description | Gurgel, Clarissa Araújo. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Wiley | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Adesão celular | pt_BR |
| Subject in Portuguese | E-caderina | pt_BR |
| Subject in Portuguese | Transição epitelial-mesenquimal | pt_BR |
| Subject in Portuguese | Imuno-histoquímica | pt_BR |
| Subject in Portuguese | Tumores odontogênicos | pt_BR |
| Title | E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1111/jop.12382 | |
| Abstract | The epithelial-mesenchymal transition (EMT) is the process where cells lose their epithelial features and acquire properties of typical mesenchymal cells. The dissociation of tumor cells due to changes in cell-cell adhesion is one of the key principles of tumor invasion and EMT. Thus, the knowledge of the molecular features of EMT in keratocyst odontogenic tumor (KOT) can provide useful markers to aid in the diagnosis and prognosis and perhaps contribute to an alternative therapeutic approach as it shows an aggressive clinical behavior and high recurrence rates. This study aimed to evaluate the EMT in KOT by the immunoexpression of E-cadherin, N-cadherin, Snail, and Slug and comparing to radicular cysts and dental follicles. | pt_BR |
| Affilliation | Federal University of Bahia. School of Dentistry. Pos-graduate of Dentistry and Health. Salvador, BA, Brazil | pt_BR |
| Affilliation | Federal University of Bahia. School of Dentistry. Department of Propaedeutics and Integrated Clinical Practicum. Surgical Pathology Laboratory. Salvador, BA, Brazil | pt_BR |
| Affilliation | Federal University of Bahia. School of Dentistry. Department of Propaedeutics and Integrated Clinical Practicum. Salvador, BA, Brazil | pt_BR |
| Affilliation | Federal University of Bahia. School of Dentistry. Department of Social and Pediatric Dentistry. Salvador, BA, Brazil | pt_BR |
| Affilliation | Federal University of Bahia. School of Dentistry. Pos-graduate of Dentistry and Health. Salvador, BA, Brazil | pt_BR |
| Affilliation | Federal University of Bahia. School of Dentistry. Department of Propaedeutics and Integrated Clinical Practicum. Salvador, BA, Brazil | pt_BR |
| Affilliation | University of São Paulo. Institute of Biomedical Sciences. Department of Anatomy, Extracellular Matrix Biology and Cellular Interaction Laboratory. São Paulo, SP, Brazil | pt_BR |
| Affilliation | Federal University of Bahia. School of Dentistry. Department of Propaedeutics and Integrated Clinical Practicum. Surgical Pathology Laboratory. Salvador, BA, Brazil | pt_BR |
| Subject | Cell adhesion | pt_BR |
| Subject | E-cadherin | pt_BR |
| Subject | Epithelial–mesenchymal transition | pt_BR |
| Subject | Immunohistochemistry | pt_BR |
| Subject | Odontogenic tumors | pt_BR |
| xmlui.metadata.dc.subject.ods | 11 Cidades e comunidades sustentáveis | |
