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2038-08-30
Sustainable Development Goals
02 Fome zero e agricultura sustentável
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EFFECT OF BASELINE MICRONUTRIENT AND INFLAMMATION STATUS ON CD4 RECOVERY POST-CART INITIATION IN THE MULTINATIONAL PEARLS TRIAL
Shivakoti, Rupak et al. | Date Issued: 2018
Author
Shivakoti, Rupak
Ewald, Erin R
Gupte, Nikhil
Yang, Wei-Teng
Kanyama, Cecilia
Cardoso, Sandra W
Santos, Breno
Supparatpinyo, Khuanchai
Badal-Faesen, Sharlaa
Lama, Javier R
Lalloo, Umesh
Zulu, Fatima
Pawar, Jyoti S
Riviere, Cynthia
Kumarasamy, Nagalingeswaran
Hakim, James
Pollard, Richard
Detrick, Barbara
Balagopal, Ashwin
Asmuth, David M
Semba, Richard D
Campbell, Thomas B
Golub, Jonathan
Gupta, Amita
Affilliation
Johns Hopkins University. School of Medicine. Department of Medicine. Baltimore, MD, USA.
Johns Hopkins Bloomberg. School of Public Health. Department of Epidemiology. Baltimore, MD, USA.
Johns Hopkins University. School of Medicine. Department of Medicine. Baltimore, MD, USA.
Johns Hopkins University. School of Medicine .Department of Medicine. Baltimore, MD, USA.
NC Lilongwe. Lilongwe, Malawi.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Hospital Nossa Senhora de Conceição. Porto Alegre, RS, Brasil.
Chiang Mai University. Chiang Mai, Thailand.
University of Witwatersrand. Department of Medicine. Johannesburg, South Africa.
Asociacion Civil Impacta Salud y Educacion. IMPACT PERU Clinical Trials Unit. Lima, Peru.
University of KwaZulu Natal. Nelson R Mandela School of Medicine. Durban, South Africa.
Johns Hopkins Research Project. Malawi College of Medicine. Kachere Rehabilitation Centre. Blantyre, Malawi.
National AIDS Research Institute. Pune, India.
Les Centres GHESKIO. Port-Au-Prince, Haiti.
YR Gaitonde Center for AIDS Research and Education. Chennai, India.
University of Zimbabwe. Harare, Zimbabwe.
University of California Davis. Department of Medicine. Sacramento, CA, USA.
Johns Hopkins University. School of Medicine. Department of Pathology. Baltimore, MD, USA.
Johns Hopkins University. School of Medicine .Department of Medicine. Baltimore, MD, USA.
University of California Davis. Department of Medicine. Sacramento, CA, USA.
Johns Hopkins University. School of Medicine .Department of Ophthalmology. Baltimore, MD, USA.
University of Colorado. School of Medicine. Division of Infectious Diseases. Department of Medicine. Aurora, CO, USA.
Johns Hopkins University. School of Medicine .Department of Medicine. Baltimore, MD, USA.
Johns Hopkins University. School of Medicine .Department of Medicine. Baltimore, MD, USA.
Abstract
Nutritional deficiency and inflammation may impact CD4+ T cell recovery during combination antiretroviral therapy (cART), particularly in resource-limited settings where malnutrition is prevalent. The aim of this study was to investigate the relationship of micronutrient and inflammation biomarkers to CD4 recovery after cART initiation.
Keywords
CD4 reconstitution
CD4 recovery
HIV
Inflammation
Micronutrients
Nutrition
 
Publisher
Elsevier
Citation
SHIVAKOTI, R. et al. Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial. Clinical Nutrition, 2018.
DOI
10.1016/j.clnu.2018.05.014
ISSN
0261-5614
Notes
NWCS 319 and ACTG PEARLS Study Team make up the group of authors.