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2020-10-17
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PLATELETS IN DENGUE INFECTION
Hottz, Eugenio et al. | Date Issued: 2011
Author
Hottz, Eugenio
Tolley, Neal D.
Zimmerman, Guy A.
Weyrich, Andrew S.
Bozza, Fernando A.
Affilliation
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Immunofarmacologia. Rio de Janeiro, RJ, Brasil.
University of Utah. Molecular Medicine Program. Salt Lake City, UT, USA.
University of Utah. Department of Internal Medicine. Salt Lake City, UT, USA.
University of Utah. Molecular Medicine Program. Salt Lake City, UT, USA / University of Utah. Department of Internal Medicine. Salt Lake City, UT, USA.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Immunofarmacologia. Rio de Janeiro, RJ, Brasil.
Abstract
Dengue has established itself as one of the world’s most common mosquito-borne viral diseases. Although it prevails in tropical areas, sustained transmission of dengue has recently occurred in Florida. Dengue viruses can induce a spectrum of symptoms and, in severe cases, mortality in approximately 1-5% of infected individuals. A hallmark of dengue infection is thrombocytopenia that associates with abnormal platelet function, which is the focus of this review.
Keywords
Dengue
Platelets
 
Publisher
Elsevier
Citation
HOTTZ, Eugenio et al. Platelets in dengue infection. Drug Discovery Today: Disease Mechanisms, v. 8, n. 1-2, p. 33-38, 2012.
DOI
10.1016/j.ddmec.2011.09.001
ISSN
1740-6765
Notes
Fernando A. Bozza. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.