| Author | Nguyen, Deanna D. | |
| Author | Maillard, Michel H. | |
| Author | Almeida, Vinicius Cotta de | |
| Author | Mizoguchi, Emiko | |
| Author | Klein, Christoph | |
| Author | Fuss, Ivan | |
| Author | Nagler, Cathryn | |
| Author | Mizoguchi, Atsushi | |
| Author | Bhan, Atul K. | |
| Author | Snapper, Scott B. | |
| Access date | 2020-04-30T20:20:14Z | |
| Available date | 2020-04-30T20:20:14Z | |
| Document date | 2007 | |
| Citation | NGUYEN, Deanna D. et al. Lymphocyte-Dependent and Th2 Cytokine-Associated Colitis in Mice Deficient in Wiskott-Aldrich Syndrome Protein. Gastroenterology, v. 133, n. 4, p. 1188-1197, Oct. 2007. | pt_BR |
| ISSN | 0016-5085 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/41054 | |
| Language | eng | pt_BR |
| Publisher | Elsevier: 12 months | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Síndrome de Wiskott-Aldrich | pt_BR |
| Subject in Portuguese | Colite | pt_BR |
| Subject in Portuguese | Linfócitos | pt_BR |
| Subject in Portuguese | Citocinas Th2 | pt_BR |
| Subject in Portuguese | Ratos deficientes | pt_BR |
| Title | Lymphocyte-dependent and Th2 cytokine-associated colitis in mice deficient in Wiskott-Aldrich syndrome protein | pt_BR |
| Type | Article | |
| DOI | 10.1053/j.gastro.2007.07.010 | |
| Abstract | Controversy exists as to whether patients with inflammatory bowel disease have an underlying immunodeficiency. We have focused on a murine model of the Wiskott-Aldrich syndrome, an immunodeficiency in which autoimmunity can manifest in the form of an inflammatory bowel disease-like illness. Wiskott-Aldrich syndrome protein (WASP) deficiency in mice results in similar clinical features. Herein, we characterized the colitis in WASP-deficient mice. | pt_BR |
| Affilliation | Massachusetts General Hospital. Gastrointestinal Unit. Boston, MA, USA / Harvard Medical School. Department of Medicine. Boston, MA, USA. | pt_BR |
| Affilliation | Massachusetts General Hospital. Gastrointestinal Unit. Boston, MA, USA / Harvard Medical School. Department of Medicine. Boston, MA, USA / Lausanne Medical School. Department of Medicine Division of Gastroenterology and Hepatology. Lausanne, Switzerland. | pt_BR |
| Affilliation | Massachusetts General Hospital. Gastrointestinal Unit. Boston, MA, USA / Harvard Medical School. Department of Medicine. Boston, MA, USA / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Massachusetts General Hospital. Gastrointestinal Unit. Boston, MA, USA / Harvard Medical School. Department of Medicine. Boston, MA, USA. | pt_BR |
| Affilliation | Hannover Medical School. Department of Pediatric Hematology/Oncology. Hannover, Germany. | pt_BR |
| Affilliation | National Institute of Health. Mucosal Immunity Section. Bethesda, Maryland, USA. | pt_BR |
| Affilliation | Massachusetts General Hospital. Center for the Study of Inflammatory Bowel Diseases. Division of Rheumatology, Allergy and Immunology. Boston, MA, USA / Harvard Medical School. Department of Medicine. Boston, MA, USA. | pt_BR |
| Affilliation | Massachusetts General Hospital. Immunopathology Unit. Boston, MA, USA / Harvard Medical School. Department of Pathology. Boston, MA, USA. | pt_BR |
| Affilliation | Massachusetts General Hospital. Gastrointestinal Unit. Boston, MA, USA / Harvard Medical School. Department of Pathology. Boston, MA, USA. | pt_BR |
| Affilliation | Massachusetts General Hospital. Gastrointestinal Unit. Boston, MA, USA / Harvard Medical School. Department of Medicine. Boston, MA, USA. | pt_BR |
| Subject | Wiskott-Aldrich Syndrome Protein | pt_BR |
| Subject | Colitis | pt_BR |
| Subject | Lymphocyte | pt_BR |
| Subject | Th2 Cytokine | pt_BR |
| Subject | Mice Deficient | pt_BR |
| e-ISSN | 1528-0012 | |
