Background: The "Health Solutions Fair: 'One Health' in the Healthy and Sustainable Territory" in Bento Gonçalves city, extreme south of Brazil, was a locus of aggregation of solutions and successful experiences using citizen science, university research, patented products and innovative ideas of public and private initiatives to transform it in to real benefits to society through the construction of intersectoral partnerships and cooperation. The background is the production of qualitative evidence for the challenges of the sustainable development objectives (SDGs) of the WHO Agenda 2030. Objectives: create spaces of regional dialogues, with technological prospecting to identify health solutions and thus enabling the activation of cooperative networks for diffusion of industrial, social and service innovations. Also identify and disseminate social, industrial and service solutions conducting the meeting between solution developers and interested citizens. Methods: organization of a fair in three moments, adding a qualitative method of data collection and analysis. First, the collection of solutions and experiences with the intersectoral interaction and the realization of partnerships; second, classification of the solutions and experiences as ODS’s objectives; third, follow up of the solutions to reach millennium developments in the RS territorio with the COSEMS and Fiocruz partnership. Results: the 'Fair' held by Fiocruz and COSEMS in Bento Gonçalves (RS) from April 22 to 25, 2019 had the effective participation of citizens, managers, researchers and entrepreneurs in their programming and in the planned activities. There were 115 presentations of successful experiences referring to 92 municipalities by the citizens. There were also 108 innovative solutions classified by social, industrial and service solutions mapped out, 34% of these data were related to ODS03 and 11% to ODS04. Conclusions: it was possible to evidence the strengthening of use of qualitative evidence in actions related to global challenges Agenda 2030 in RS territory and the use of this by citizens and producers to find out solutions for the decision making at SDGs work agenda intersectorally in the southest part of Brazil.The participation of society, industry and government is considered an important tool to effectively achieve the goals of the WHO Agenda.