Browsing by Author "Moreira, Diogo Rodrigo Magalhães"
Now showing items 11-30 of 54
-
Betulinic acid derivative BA5, a dual NF-kB/calcineurin inhibitor, alleviates experimental shock and delayed hypersensitivity
Meira, Cássio Santana et al. | Date Issued: 2017 -
Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization
Meira, Cássio Santana et al. | Date Issued: 2019 -
A betulinic acid derivative, BA5, induces G0/G1 cell arrest, apoptosis like-death, and morphological alterations in leishmania sp
Magalhães, Tatiana Barbosa dos Santos et al. | Date Issued: 2022 -
Chemical and pharmacological properties of decoquinate: a review of its pharmaceutical potential and future perspectives
Souza, Tainá Santos et al. | Date Issued: 2022 -
Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents
Macedo, Taís Soares et al. | Date Issued: 2016 -
Conjugation of N-acylhydrazone and 1,2,4-oxadiazole leads to the identification of active antimalarial agents
Santos Filho, José Maurício dos et al. | Date Issued: 2016 -
Derivados amidínicos do ácido betulínico são potentes e seletivos agentes anti-T. cruzi por exercerem ação parasiticida irreversível e induzirem necrose
Anjos, Pâmela S. dos et al. | Date Issued: 2016 -
Design, synthesis and biological evaluation of 3-[4-(7-chloro-quinolin-4-yl)-piperazin-1-yl]-propionic acid hydrazones as antiprotozoal agents.
Inam, Afreen et al. | Date Issued: 2014 -
Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents
Santos Filho, José Maurício dos et al. | Date Issued: 2009 -
Design, synthesis and structure-activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities
Cardoso, Marcos Veríssimo de Oliveira et al. | Date Issued: 2015 -
Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi
Silva Júnior, E. F. et al. | Date Issued: 2016 -
Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death
Silva, Elany Barbosa da et al. | Date Issued: 2017 -
Dimeric flavonoids from Arrabidaea brachypoda and assessment of their anti-Trypanosoma cruzi activity.
Rocha, Cláudia Quintino da et al. | Date Issued: 2014 -
Efeito dos extratos de valeriana officinalis na citotoxicidade da rotenona in vitro e na depressão alastrante cortical in vivo
Brito, Ana Paula Amaral de | Date Issued: 2015Os astrócitos são o tipo celular mais numeroso no sistema nervoso central (SNC). Eles exercem suporte estrutural, trófico, e metabólico para neurônios e modulam a atividade sináptica. Então, o prejuízo nestas funções dos ... -
Evaluation of naphthoquinones identified the acetylated isolapachol as a potent and selective antiplasmodium agent
Moreira, Diogo Rodrigo Magalhães et al. | Date Issued: 2015 -
Extrato etanólico da Physalis angulata inibe o crescimento do T. cruzi e a proliferação espontânea de linhagem leucêmica infectada pelo HTLV-1
Oliveira, Francine S. de et al. | Date Issued: 2016A doença de Chagas e o HTLV-1 são doenças infecciosas predominantes nos trópicos. Os medicamentos disponíveis para o tratamento destas doenças não são adequados ou eficazes. Na busca de novos medicamentos, produtos naturais ... -
Fármacos com ação dual anti-Trypanosoma cruzi e imunomoduladora: Uma nova abordagem para o tratamento da miocardiopatia chagásica crônica
Meira, Cássio Santana | Date Issued: 2018A doença de Chagas é uma zoonose causada pelo protozoário hemoflagelado Trypanosoma cruzi, que afeta milhões de pessoas na America Latina. No Brasil e em muitos países, o tratamento dessa enfermidade se baseia na utilização ... -
In vitro and in vivo antiparasitic activity of Physalis angulata L. concentrated ethanolic extract against Trypanosoma cruzi
Meira, Cássio Santana et al. | Date Issued: 2015 -
In vitro and In Vivo Immunomodulatory Activity of Physalis angulata Concentrated Ethanolic Extract
Daltro, Sérgio Ricardo Teixeira et al. | Date Issued: 2020 -
In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N-Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis
Silva, Dahara Keyse Carvalho et al. | Date Issued: 2020