Browsing by Author "Barreiro, Eliezer J."
Now showing items 1-12 of 12
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Anti-inflammatory effects of LASSBio-998, a new drug candidate designed to be a p38 MAPK inhibitor, in an experimental model of acute lung inflammation
Lima, Aline C. Brando et al. | Date Issued: 2011 -
Design, synthesis, and pharmacological evaluation of N-acylhydrazones and novel conformationally constrained compounds as selective and potent orally active phosphodiesterase-4 inhibitors
Kümmerle, Arthur E. et al. | Date Issued: 2012 -
Design, synthesis, structural characterization and in vitro cytotoxic activity of mononuclear Ru(II)complexes
Thota, Sreekanth et al. | Date Issued: 2016Compostos contendo platina demonstraram potencial antineoplásico, mas suas aplicações clínicas foram limitadas pela alta toxicidade. Complexos contendo rutênio são conhecidos há muito tempo por serem adequados para aplicações ... -
Discovery of LASSBio-772, a 1,3-benzodioxole N-phenylpiperazine derivative with potent alpha 1A/D-adrenergic receptor blocking properties
Romeiro, Luiz A. S. et al. | Date Issued: 2011 -
Evaluating the prophylactic potential of the phtalimide derivative LASSBio 552 on allergen-evoked inflammation in rats
Neves, Josiane S. et al. | Date Issued: 2005 -
Inside the FDA: the business and politics behind the drugs we take and the food we eat
Barreiro, Eliezer J. | Date Issued: 2008 -
LASSBio-468: a new achiral thalidomide analogue which modulates TNF-a and NO production and inhibits endotoxic shock and arthritis in an animal model
Moreira, Magna S. Alexandre et al. | Date Issued: 2005 -
Ru(II) Compounds: Next-Generation Anticancer Metallotherapeutics?
Thota, Sreekanth et al. | Date Issued: 2018Terapêuticas baseadas em metais são uma classe preciosa de medicamentos na pesquisa oncológica que inclui exemplos de medicamentos teranósticos, que são ativos tanto em aplicações diagnósticas, especificamente de imagem, ... -
Synthesis and characterization of the atropisomeric relationships of a substituted N-phenyl-bipyrazole derivative with anti-inflammatory properties
Veloso, Marcia P. et al. | Date Issued: 2012 -
Synthesis and pharmacological evaluation of novel phenyl sulfonamide derivatives designed as modulators of pulmonary inflammatory response
Barbosa, Maria Letícia de Castro et al. | Date Issued: 2012 -
Synthesis, characterization, DNA binding, DNA cleavage, protein binding and cytotoxic activities of Ru(II) complexes
Thota, Sreekanth et al. | Date Issued: 2016Relatamos a síntese de novos compostos de Ru(II) (Ru-1 a Ru-8) contendo ligantes R-pdc, 4-Cl-pbinh (onde R = 4-CF3, 4-F, 4-OH pdc = 3-fenil-5-(1H-pirrol-2-il)-4,5-di-hidro-1H-pirazol-1-carbotioamida, pbinh = fenoxibenzilideno ... -
Synthesis, Pharmacological Profile and Docking Studies of New Sulfonamides Designed as Phosphodiesterase-4 Inhibitors
Nunes, Isabelle Karine da Costa et al. | Date Issued: 2016