Browsing by Author "Lechuga, Guilherme Curty"
Now showing items 1-16 of 16
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Bioactivity of Novel Pyrazole-Thiazolines Scaffolds against Trypanosoma cruzi: Computational Approaches and 3D Spheroid Model on Drug Discovery for Chagas Disease
Lara, Leonardo da Silva et al. | Date Issued: 2022 -
Chagas disease diagnosis with Trypanosoma cruzi-exclusive epitopes in GFP
Durans, Andressa da Matta et al. | Date Issued: 2024 -
Epitope mapping of the diphtheria toxin and development of an ELISA-specific diagnostic assay
De-Simone, Salvatore Giovanni et al. | Date Issued: 2021 -
Evaluation a prototype rapid test for chronic Chagas disease in an endemic region of the Brazilian Amazon
Dias, Evandro da Rocha et al. | Date Issued: 2023 -
Humoral immune response to SARS-CoV-2 spike protein receptor-binding motif linear epitopes
Monteiro, Maria Eduarda Silva et al. | Date Issued: 2024 -
Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi
Lechuga, Guilherme Curty et al. | Date Issued: 2016 -
A multi-epitope protein for high-performance serodiagnosis of chronic Chagas disease in ELISA and lateral flow platforms
Dias, Evandro da Rocha et al. | Date Issued: 2024 -
Nicastrin-Like, a Novel Transmembrane Protein from Trypanosoma cruzi Associated to the Flagellar Pocket
Lechuga, Guilherme Curty et al. | Date Issued: 2021 -
Otimização e atividade biológica de derivados de pirazol sobre Trypanosoma cruzi: análise computacional, ensaios de reversibilidade e modelo de cultivo 3D como potenciais ferramentas preditivas de eficácia
Orlando, Lorraine Martins Rocha | Date Issued: 2021A doença de Chagas é uma doença negligenciada que acomete 6-7 milhões de indivíduos no mundo, com a estimativa de 1,2 a 4 milhões de indivíduos infectados no Brasil. Esta doença centenária causa elevada morbidade e ... -
Pan-Drug Resistant Acinetobacter baumannii, but Not Other Strains, Are Resistant to the Bee Venom Peptide Melittin
Carvalho, Karyne Rangel et al. | Date Issued: 2020 -
SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites
Lechuga, Guilherme Curty et al. | Date Issued: 2021 -
Small Angle X-ray Scattering, Molecular Modeling, and Chemometric Studies from a Thrombin-Like (Lmr-47) Enzyme of Lachesis m. rhombeata Venom
De Simone, Salvatore Giovanni et al. | Date Issued: 2021 -
Structural Optimization and Biological Activity of Pyrazole Derivatives: Virtual Computational Analysis, Recovery Assay and 3D Culture Model as Potential Predictive Tools of Effectiveness against Trypanosoma cruzi
Orlando, Lorraine Martins Rocha et al. | Date Issued: 2021 -
The combination therapy of meglumine antimoniate and oxiranes (epoxy-α-lapachone and epoxymethyl-lawsone) enhance the leishmanicidal effect in mice infected by Leishmania (Leishmania) amazonensis
Oliveira, Luiz Filipe Gonçalves et al. | Date Issued: 2019 -
Trypanosoma cruzi Presenilin-like transmembrane aspartyl protease: charactherization and cellular localization
Lechuga, Guilherme Curty et al. | Date Issued: 2020 -
Vias de atuação do epoxi-α-lapachona e epoximetil-lausona sobre as proteínas de Leishmania (Viannia) braziliensis
Oliveira, Adriane da Silva | Date Issued: 2020Na busca de fármacos mais eficazes e seguros para o tratamento das leishmanioses, compostos derivados de naftoquinonas como epoxi-α-lapachona e epoximetil-lausona surgem como alternativas promissoras. Neste trabalho ...