Browsing by Author "Leite, Ana Cristina Lima"
Now showing items 1-20 of 39
-
2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity
Cardoso, Marcos Veríssimo de Oliveira et al. | Date Issued: 2019 -
2-Iminothiazolidin-4-ones arrest Trypanosoma cruzi growth and impair trypomastigote development in macrophages
Meira, Cássio Santana et al. | Date Issued: 2012 -
2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation.
Cardoso, Marcos Veríssimo de Oliveira et al. | Date Issued: 2014 -
Anti-liver cancer activity in vitro and in vivo induced by 2-pyridyl 2,3-thiazole derivatives
Silva, Thiago David dos Santos et al. | Date Issued: 2017 -
Antitumor and immunomodulatory activities of thiosemicarbazones and 1,3-Thiazoles in Jurkat and HT-29 cells
Santos, Thiago André Ramos dos et al. | Date Issued: 2016 -
Approaches for the development of new anti-Trypanosoma cruzi agents
Moreira, Diogo Rodrigo Magalhães et al. | Date Issued: 2009 -
Aryl thiosemicarbazones: In vitro and immunomodulatory activities against L. amazonensis
Silva, Aline Caroline da et al. | Date Issued: 2017 -
Avaliação in vitro do perfil de morte celular de Trypanosoma Cruzi frente à série inédita de Tiossemicarbazonas
Silva, Sophia Bezerra da et al. | Date Issued: 2018Na patologia da Doença de Chagas, a imunorregulação, o controle da carga parasitária e o processo inflamatório são aspectos relacionados à morte celular. A morte celular pode ser programada como, por exemplo, pela apoptose, ... -
Compound profiling and 3D-QSAR studies of hydrazone derivatives with activity against intracellular Trypanosoma cruzi
Costa, Lívia Bandeira et al. | Date Issued: 2016 -
Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death
Moreira, Diogo Rodrigo Magalhaes et al. | Date Issued: 2014 -
Cytotoxic and toxicological effects of phthalimide derivatives on tumor and normal murine cells
Ferreira, Paulo Michel Pinheiro et al. | Date Issued: 2015Onze derivados da ftalimida foram avaliados quanto a sua atividade antiproliferativa em células tumorais e normais e possíveis efeitos tóxicos. Avaliou-se a citotoxicidade contra tumores murinos (células de Sarcoma 180 ... -
Design, synthesis and biological evaluation of 3-[4-(7-chloro-quinolin-4-yl)-piperazin-1-yl]-propionic acid hydrazones as antiprotozoal agents.
Inam, Afreen et al. | Date Issued: 2014 -
Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents
Santos Filho, José Maurício dos et al. | Date Issued: 2009 -
Design, synthesis and structure-activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities
Cardoso, Marcos Veríssimo de Oliveira et al. | Date Issued: 2015 -
Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death
Silva, Elany Barbosa da et al. | Date Issued: 2017 -
Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles
Santiago, Edna de Farias et al. | Date Issued: 2014 -
In vitro and in vivo activities of multi-target phtalimido-thiazoles on Schistosomiasis mansoni
Miranda Filho, Carlos André Laranjeira et al. | Date Issued: 2020 -
Intermolecular interaction of thiosemicarbazone derivatives to solvents and a potential Aedes aegypti target
Silva, João Bosco Paraiso da et al. | Date Issued: 2015 -
Investigação Farmacológica de um novo Inibidor da Cruzaína em Modelo Animal Infectado com o Trypanosoma Cruzi (Cepa Y)
Costa, Salvana Priscylla Manso et al. | Date Issued: 2009Introdução: O desenvolvimento de novas drogas antichagásicas é uma área crucial para o combate da doença desde que o Benznidazol é ineficaz na fase crônica e de toxicidade pronunciada. Um dos mais promissores alvos para ... -
New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi
Gomes, Paulo André Teixeira de Moraes et al. | Date Issued: 2016