Browsing by Author "Moreira, Diogo Rodrigo Magalhães"
Now showing items 1-20 of 54
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2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity
Cardoso, Marcos Veríssimo de Oliveira et al. | Date Issued: 2019 -
2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation.
Cardoso, Marcos Veríssimo de Oliveira et al. | Date Issued: 2014 -
Anti-inflammatory activity of SintMed65, an N-acylhydrazone derivative, in a mouse model of allergic airway inflammation
Cerqueira, Jéssica Vieira et al. | Date Issued: 2019 -
Antiparasitic evaluation of betulinic acid derivatives reveals effective and selective anti-Trypanosoma cruzi inhibitors
Meira, Cássio Santana et al. | Date Issued: 2016 -
Antitumor and immunomodulatory activities of thiosemicarbazones and 1,3-Thiazoles in Jurkat and HT-29 cells
Santos, Thiago André Ramos dos et al. | Date Issued: 2016 -
Approaches for the development of new anti-Trypanosoma cruzi agents
Moreira, Diogo Rodrigo Magalhães et al. | Date Issued: 2009 -
Aryl thiosemicarbazones: In vitro and immunomodulatory activities against L. amazonensis
Silva, Aline Caroline da et al. | Date Issued: 2017 -
Atividade antimalárica, espectro e mecanismo de ação de compostos de rutênio e platina com a cloroquina
Macedo, Taís Soares | Date Issued: 2016INTRODUÇÃO: A malária é uma das doenças infecciosas de maior incidência e que mais leva a óbito no mundo. Os medicamentos disponíveis são capazes de combater o parasita no ciclo intraeritrocítico, no entanto há cepas ... -
Avaliação farmacológica da tiossemicarbazona triapina na infectividade do T. cruzi e na proliferação espontânea em células leucêmicas infectadas pelo HTLV-1
Oliveira, Francine S. de et al. | Date Issued: 2016A Triapina é um quelante de ferro que inibe a proliferação de diversas linhagens tumorais. Doenças infecciosas como a doença de Chagas e o HTLV-1 permanecem sem um tratamento adequado, tornando necessária a busca de novos ... -
Avaliação in vitro do perfil de morte celular de Trypanosoma Cruzi frente à série inédita de Tiossemicarbazonas
Silva, Sophia Bezerra da et al. | Date Issued: 2018Na patologia da Doença de Chagas, a imunorregulação, o controle da carga parasitária e o processo inflamatório são aspectos relacionados à morte celular. A morte celular pode ser programada como, por exemplo, pela apoptose, ... -
Betulinic acid derivative BA5, a dual NF-kB/calcineurin inhibitor, alleviates experimental shock and delayed hypersensitivity
Meira, Cássio Santana et al. | Date Issued: 2017 -
Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization
Meira, Cássio Santana et al. | Date Issued: 2019 -
A betulinic acid derivative, BA5, induces G0/G1 cell arrest, apoptosis like-death, and morphological alterations in leishmania sp
Magalhães, Tatiana Barbosa dos Santos et al. | Date Issued: 2022 -
Chemical and pharmacological properties of decoquinate: a review of its pharmaceutical potential and future perspectives
Souza, Tainá Santos et al. | Date Issued: 2022 -
Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents
Macedo, Taís Soares et al. | Date Issued: 2016 -
Conjugation of N-acylhydrazone and 1,2,4-oxadiazole leads to the identification of active antimalarial agents
Santos Filho, José Maurício dos et al. | Date Issued: 2016 -
Derivados amidínicos do ácido betulínico são potentes e seletivos agentes anti-T. cruzi por exercerem ação parasiticida irreversível e induzirem necrose
Anjos, Pâmela S. dos et al. | Date Issued: 2016 -
Design, synthesis and biological evaluation of 3-[4-(7-chloro-quinolin-4-yl)-piperazin-1-yl]-propionic acid hydrazones as antiprotozoal agents.
Inam, Afreen et al. | Date Issued: 2014 -
Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents
Santos Filho, José Maurício dos et al. | Date Issued: 2009 -
Design, synthesis and structure-activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities
Cardoso, Marcos Veríssimo de Oliveira et al. | Date Issued: 2015